We welcome Dr Michelle Petri Johns Hopkins Rheumatology to our rheum-renal conference ⛓️ article: pubmed.ncbi.nlm.nih.gov/25861455/

NEW 🔥Local botulinum toxin type A injection has beneficial therapeutic effects on Raynaud’s phenomenon and digital ulcers in patients with #SystemicSclerosis 👉bit.ly/3JPfx3t

#Methotrexate does *not* cause liver fibrosis pubmed.ncbi.nlm.nih.gov/36702175/ #RA #psoriaticarthritis #rheumatoidarthritis

Clinical phenotypes in ANCA asociated interstitial lung disease: - 100 patients. Retrospective study. - 3 groups: MPA, unclassifiable vasculitis, IPF (ANCA+). - Unclassifiable vasculitis tended to have a better survival

More evidence on JAK inhibitors in dermatomyositis: - Open label. 16 patients. 88% cutaneous, 56% muscle, 44% both. - Improvement in CDASI ➡ 27 (basal) ➡ 14 (3 months) ➡ 5 (1.8 years). - 1 died (MDA5 with ILD), 2 relapsed (muscle disease). pubmed.ncbi.nlm.nih.gov/36356704/

Our analysis of myositis specific and associated antibodies (MSA/MAA) detected by line blot in our Immunology lab between 2018 -2020 - 130 samples ➡ 164 MSA/MAA. - 51.8% were classified as clinical true + (CTP) (associated to their disease) and 48.2% as clinical false + (CFP).

#ClinicalPearl #MedEd #MedTwitter Elderly woman with long-standing hand pain. What do you think? hint look at L2nd MCP. Bonus - what about bone quality

Review on scleromyositis: - No validated definition. - Aldolase is more frequently elevated than CK. - Antibodies: anti-PM/Scl, -Ku, -U1-RNP, -U3-RNP, - RuvBL1/2, -SMN - Muscle biopsy: Vasculopathy, fibrosis, myofiber necrosis. - Be careful with steroids and SSc renal crisis.

Que mala atención de Volaris Merida

#MyositisPearl 8: A subtype of #Myositis is Immune Mediated Necrotizing Myopathy (#IMMM). It is about 20% of all #IIM. It is associated with anti-SRP (1/3rd) & anti-HMGCR (1/3rd) Myositis Antibody. 1/3rd Ab negative. Leads to severe muscle weakness, very high CK and disability.

Peripheral Blood Biomarkers for Rheumatoid Arthritis-Associated Interstitial Lung Disease: A Systematic Review pubmed.ncbi.nlm.nih.gov/36852564/

Tofacitinib May Reduce Interstitial Lung Disease Risk in RA Tofacitinib (Xeljanz) in patients with RA stood out among several other biologic and targeted sDMARDs when it came to the incidence of ILD, a retrospective cohort study showed. bit.ly/3Zm4Jxw

Revisión narrativa 📚 de los tratamientos disponibles para artritis psoriásica por dominios y enfermedades asociadas. Gran trabajo de Gizem Ayan André Ribeiro Betül Macit Dr. Fabian Proft GRAPPA Network - Official 👏🏻 Enlace abierto 🔓 pdf.sciencedirectassets.com/272059/AIP/1-s…

Data from 'real-world' experience suggest that Nintedanib could be helpful for patients who start treatment after presenting with ILD acute exacerbation decreasing the occurrence of recurrent exacerbations and prolonging survival. #pulmonaryfibrosis nature.com/articles/s4159…

SGLT2 inhibitor (empagliflozin) given in a lupus mouse (MRL/lpr) model showed a renoprotective effect suggesting the value of non-immunosuppressive therapies to improve renal function. Showed less -dsDNA Abs, proteinuria, renal nephritis damage bit.ly/3DKMv0E

Many treatments for seronegative #spondyloarthropathy. And #psoriatic #arthritis But what to choose and when and for whom?

Full read review of Catastrophic Antiphospholipid Syndrome (CAPS) bit.ly/3Sg2xaE

A_3 pulley with slight tenosynovitis صوره من ورشه العمل.

ARTHRITIS IMAGING Free Preview cdn.shopify.com/s/files/1/0550…

Nailfold Capillaroscopy correlated w/ cardiac ECHO in Systemic Sclerosis. NFC & ECHOs studied in 30 SSc pts. Systolic & diastolic dysfunction most common in late SSc NFC patterns. Cardiac dysfunction seen w/ low capillary density, avascular areas, cap neoangiogenesis