Native MS-guided lipidomics to define endogenous lipid microenvironments of eukaryotic receptors and transporters nature.com/articles/s4159…

Coupling and Activation of the β1 Adrenergic Receptor - The Role of the Third Intracellular Loop pubs.acs.org/doi/full/10.10…

Congratulations to my fantastic team and collaborators nature.com/articles/s4146…

Did you know there are more than bilayer #membranes in nature? Meet the #archaeal monolayer and its surprising mechanical properties! New #preprint! (1/7)

A machine learning system that simulates proteins with more than 10,000 atoms with quantum accuracy. nature.com/articles/s4158…

Bayesian nonparametric analysis of residence times for protein-lipid interactions in Molecular Dynamics simulations biorxiv.org/content/10.110…

Super interesting work and food for thought!

Membrane curvature association of amphipathic helix 8 drives constitutive endocytosis of GPCRs biorxiv.org/content/10.110…

This is one of the most amazing technologies I've seen--when I saw the bioRxiv paper I thought: "Wow why didn't I think of that?!"

Super excited to preprint our work on developing a Biomolecular Emulator (BioEmu): Scalable emulation of protein equilibrium ensembles with generative deep learning from Microsoft Research AI for Science. #ML #AI #NeuralNetworks #Biology #AI4Science biorxiv.org/content/10.110…

📢 New #preprint describing our community effort to share #plumed tutorials arxiv.org/abs/2412.03595 ! Explore the tutorials at plumed-tutorials.org

Conformational coupling between extracellular and transmembrane domains modulates holo-adhesion GPCR function nature.com/articles/s4146…

Huge 🚨Lipid Time🚨 for #compchem Community! The release of the new set of Siewert-Jan Marrink 3 parametrizations for a wide range of lipid types is now out on ChemRxiv #LipidTime doi.org/10.26434/chemr…

Wow! nature.com/articles/s4146…

A cryptic pocket in CB1 drives peripheral and functional selectivity nature.com/articles/s4158…

Wow, wow, wow! Sensing ceramides by CYSLTR2 and P2RY6 to aggravate atherosclerosis nature.com/articles/s4158…

Encoding and decoding selectivity and promiscuity in the human chemokine-GPCR interaction network doi.org/10.1016/j.cell…

G Protein Selectivity in Dopamine Receptors is Determined before GDP Release pubs.acs.org/doi/full/10.10…