orthweinlab
@orthweinlab1
DNA repair lab located at the Winship Cancer Center as part of the Department of Radiation Oncology, Emory @EmoryUniversity @WinshipatEmory @Emorymedicine
ID: 4267432587
https://med.emory.edu/departments/radiation-oncology/research-laboratories/alexandre-orthwein/ 24-11-2015 21:13:41
1,1K Tweet
636 Followers
726 Following
It’s out! After 14+ long years of enrollment, analysis and follow up the CoMMpass trial is published in full format nam11.safelinks.protection.outlook.com/?url=https%3A%…. Thanks to J Keats, all the investigators, Multiple Myeloma RF and to the patients who were part of this landmark study.
🚨 Excited to share our latest paper in Cell identifying how under-replicated chromosomes in micronuclei become shattered by the Fanconi anemia pathway during mitosis. This work was led by UTSW Graduate School of Biomedical Sciences student Justin Engel. 🧵 (1/13): cell.com/cell/fulltext/…
One of those super proud PI days! I am so excited for Emory Biochemistry Cell & Developmental Biology student Nearly Dr. Carly Lancaster to defend her PhD on Friday! Reach out to me or Carly if you would like a Zoom link!! Carly already has a job lined up in biotech! She is amazing!
Delighted to announce that my first first-author paper „DNA polymerase α-primase facilitates PARP inhibitor-induced fork acceleration and protects BRCA1-deficient cells against ssDNA gaps“ is on Nature Communications now! Check out what we found!🧵1/7 doi.org/10.1038/s41467…
🧬🔬 Our paper on FANCM's DNA binding mechanism is out in Nucleic Acids Res. FANCM is crucial for DNA repair and cancer cell survival in ALT Lara Abbouche Rohan Bythell-Douglas hildapickett academic.oup.com/nar/advance-ar…
My group had a small part in this collaborative effort lead by Huaiying Zhang to study the role of SUMOylation (in the absence of PML) in Alternative Lengthening of Telomeres in cancer cells. genesdev.cshlp.org/content/38/13-… Short tweetorial here: x.com/rongweiz/statu… by Rongwei Zhao
just for the pleasure of it, the fine choreography of epithelial cell migration with a PI3K mutation. This is the complex behavior we have to drug to treat cancer ... Movie from Lucien Hinderling . Switch sound on.
I'm incredibly fortunate to be a cancer researcher Université de Sherbrooke and to tackle a challenge that hits so close to home. Thank you Canadian Cancer Society and donors for supporting patients and researchers! Grateful to be part of this journey towards a cure. 💛
Now that we're entering faculty job season, I want to reshare my ✨job search advice doc✨. It compiles all the super helpful advice I received from mentors & includes my own experiences on the market. Best of luck out there, everyone - you got this! 💪 helpimascientist.com/wp-content/upl…
Great job, Ash, Pia Reichl, and Ross Chapman, and congrats on this amazing paper! 😃 nature.com/articles/s4159…
Excited to share our lab's latest research, out today NatureStructMolBiol, which describes how 53BP1 controls DNA Repair in class-switching B cells & BRCA1 mutant cancers. Final article can be found here: nature.com/articles/s4159…; & the following thread walks you through the details
Very exited about my first day as a faculty member at the Department of Radiation Oncology Emory School of Medicine. Look forward to continued and new collaborations with my amazing mentors, colleagues, and scholars Reshma Jagsi Mylin Torres Ilana G and more!
New research, in collab. with Pierre Cordelier at CRCT-Oncopole, highlights the role of Cytidine Deaminase (CDA) in mitochondrial function & metabolism in pancreatic cancer cells disq.us/t/4qfb3pj in Communications Biology It was a pleasure Pierre to work with your team on this project!