🚨Please help us to help our patients! Everyone involved in the care of patients with #rheumatic diseases #RMDs : take a moment to explore the awareness of #EULAR #cardiovascular disease #CVD guidelines:
lnkd.in/dhEBtkiD EMEUNET EULAR Jette Primdahl

💡Safety, Pharmacokinetics, Biomarker Response, and Efficacy of E6742, a Dual Antagonist of Toll-Like Receptors 7 and 8, in a First-in-Patient, Randomized, Double-Blind, Phase 1/2 Study in Systemic #Lupus 🦋Erythematosus | medRxiv

👀📖 medrxiv.org/content/10.110…

💡 #APLAR2024 information💡
Early 🐦 Registration and abstract submission has been extended👇

If you are a member of #AYR , there’s a chance for travel grants supported by APLAR 😉👇

I’ve submitted my abstract while unexpected extra night stay in Dubai😂🙌

Japan College of Rheumatology #JSTAR

📢 Proud to see this important, timely comment by Dr. Laura Esserman & Douglas Yee MD just published in Nature Medicine. I 💯 agree: Science & medical groups should stop holding conferences in anti-choice states. Abortion IS healthcare! #WomensRights
Please RT!
nature.com/articles/s4159…

🌟NEW in Nature Medicine: In 6 patients w/ #RheumatoidArthritis , the CD19xCD3 BITE #blinatumomab ⬇️ disease activity & ⬇️ autoantibodies. Work led by #GeorgSchett Ricardo Grieshaber-Bouyer FAU Erlangen-Nbg. Similar n of 1 report in systemic sclerosis published earlier this week. nature.com/articles/s4159…

I am stuck in Dubai for one night due to my delayed flight✈️ and transit issue😂

良いネタができたゎ~ｱﾊﾊ😇
#ISSjD2024
#なかなか帰れない 🏠

🇮🇹The first paper of the Italian Registry of #pregnancy in #rheumaticdiseases is out!🤰
Cannot express enough gratitude & pride to
🙏outstanding investigators collecting data since 2018
🙏SIR - Società Italiana di Reumatologia for the support
🙏>1000 patients for participating
rmdopen.bmj.com/content/10/2/e…

Thank you ISSjD2024 for organizing this wonderful symposium😊🙌
It was a pleasure to meet twitter friends in person with shared interest #SjD #Sjogrens ✨Hope to see everyone again in future congresses‼️
#ISSjD2024
✈︎

#Sjogrens disease “endotypes➡️towards precision medicine”
🔑papers📖👇
① symptom based…doi.org/10.1016/S2665-…
② transcriptional based…doi.org/10.1038/s41467…
③ combination…doi.org/10.1016/S2665-…

👉guides potential future treatment strategies✨

#ISSjD2024

A new tool for stratifying children with suspected Sjögren's disease

Linked Comment by Coziana Ciurtin & Elizabeth C Jury Jury Lab thelancet.com/journals/lanrh…

#BSR24

👉BSR guidelines on Sjögren

🔸USS of salivary glands is useful but does not substitute biopsy
🔸Measure ENA if ANA is negative
🔸Biomarkers for lymphoma development
🔸Biomarkers that predict disease progression and extra-glandular disease

#sjogren

Clinical trials in #Sjogrens disease👇

Newly established composite endpoints CRESS and STAR, because ESDDAI response were seen in placebo group.

#ISSjD2024

Cintia de Paiva mixing us up, showing NO differences in transcriptomic changes seen in #Sjogren ’s and non-Sjögren’s drye eye, unlike vs. healthy controls. Is eye inflammation a consequence of ocular surface dryness, regardless of the mechanism/origin? #ISSjD2024 ISSjD2024

I’ve registered😊🙌
See you in Singapore👍

🌟Salivary gland US→G0~G3, F graded by B-mode
👉Anti-SSA testing with US scoring could rule out the SjD diagnosis.(but if pt have sicca, still recommend biopsy)

Interesting that there are quite a lot of abstracts about gland US👀
#ISSjD2024

Reference😊
👉📖doi.org/10.1111/odi.14…
#ISSjD2024

Oral complications(candida, missing 🦷 ) are seen more frequently and salivary function is lower in #SjD pt compared to sicca non-SjD
👉recommendation of topical fluoride use differs among each guidelines. Topical fluoride have preventative role in dental caries process.
#ISSjD16

Ana Vieira personal view on the impact of #SjD in the person as a WHOLE. Impactful. As #Sjogrens . #ISSjD2024 ISSjD2024 Sjögren’s Expertise Center Groningen Sjögren Europe

Day2 soon starting from a patients point of view👀✨

🌞4時半に目が覚めた。時差ボケ🙃
#ISSjD16

Day1🔑note lecture ref📖 “Immune system adaptation during gender-affirming testosterone treatment”👇
→pDC ⬇️over transition, with phenotypic changes ⬇️IFN responses.
Cross regulation of typeI IFN and TNFa is influenced by sex hormone🚺🚹
👏
#ISSjD16
📖doi.org/10.1016/j.jri.…