1/16 Why does cirrhosis predispose to "bacterial translocation"? I have long heard that this is the mechanism of spontaneous bacterial peritonitis (SBP), but I hadn't understood why cirrhosis leads to more of it. [Or where the bacteria translocate to...] Let's have a look.

#CGH4ALL CGH 📣 🔥 Diverticular Disease & Cancer Risk 🔍 🚨 Increased cancer risk in patients w/ complicated diverticulitis! 📉  👀 Is it time to change practice? 🔗 doi.org/10.1016/j.cgh.… Reported by Raghav Bassi, MD Mohamedtaki A. Tejani Andrew Elden MD Sanjeevani Tomar, MD

#CGH4ALL 💭imagine living in a 🌎 w/ standardized objective definition of transmural healing in Crohn's disease (CD) 🔖Check out the newly developed MRI score🩻to assess therapeutic efficacy in CD in CGH 🎩 to the authors 🔗doi.org/10.1016/j.cgh.… Report Nishant Aggarwal, MD

Is it time to redefine normal limits of ALT?

#CGH4ALL CGH 📣 ♎ Familial Adenomatosis Polyposis surgery ✂️ 👀How does IRA compare w/ IPAA in terms of risk of Desmoid Tumor? 🌟Data from European FAP Consortium Know more about this here 👇 🔗 doi.org/10.1016/j.cgh.… #Gitwitter #Colorectal Reported by Talal khurshid Bhatti

#CGH4ALL CGH 📣 Is there a subgroup of IBD patients at higher risk of kidney failure? 🫘 Apart from hydro-electrolytic disturbances in the acute setting, colectomy can increase the risk of chronic kidney disease too! 😰 🔗 cghjournal.org/article/S1542-… Yuanhang Yang

#CGH4ALL CGH 📣 🔥 The use of computer-aided detection (CADe) in Endoscopy 💻 🚀 CADe increases ADR and APC vs. traditional colonoscopy 📈 🔗 doi.org/10.1016/j.cgh.… Report by Raghav Bassi, MD Pejman Solaimani, MD Monica Saumoy MD Arnold Tabuenca UC Riverside Anas M. Kawayeh, M.D @gbsaff

#CGH4ALL CGH 📣 A multicenter cohort study studies the association between LSM trajectory📈 & serious clinical events🤮 in PBC! Median LSMs ~ 2 and time between LSMs ~2 years 🚫if cirrhosis complications or LT 🔗 cghjournal.org/article/S1542-… Report by Zaid Ansari Elliot Tapper

Chronic abdominal distension and bloating - all you need to know ⭐️ 📸: Chuma G. Obineme, MD

#CGH4ALL📣 💥 💡 📈 Rising alcohol consumption -> how does it affect the burden of alcohol associated HCC around the 🌍 ? Deep dive into clinical presentations/outcomes CGH🔥! 🔗 doi.org/10.1016/j.cgh.… #HCC #alcohol #GITwitter Reported by Ifrah Fatima Hanna Blaney, MD, MPH

#CGH4ALL CGH 📣 🔥 The recent conditional approval by the FDA of Resmetirom presents a much-anticipated therapeutic option for patients with noncirrhotic advanced MASH🎯 📚 Read more about its clinical applications 🔗 doi.org/10.1016/j.cgh.… Report by Raghav Bassi, MD

#CGH4ALL Is continuation of UST safe in pregnancy? This new 📃evaluated pregnancy outcomes, developmental milestones, UST clearance and infections in UST-exposed infants. Check out the NEXUS study from 🇩🇰&🇳🇱 🔗doi.org/10.1016/j.cgh.… Summary by Nishant Aggarwal, MD

#CGH4ALL This week, we've covered 3 new CGH publications that cover the use of VDZ and UST in pregnancy🤰 🔖Our associate editor Joana Torres 🇵🇹 beautifully provides insights learned in this editorial 🔗doi.org/10.1016/j.cgh.… Summary by Nishant Aggarwal, MD

💜#GITeam #CRSurgery Join us for a convo led by Stefan Holubar MD MS Aline Charabaty, MD, FACG, AGAF 🏁Stages to IPAA in UC - can we stop before the finish line? 🆓#CME👉🏽bit.ly/MNIBD24-25 🗳️Poll👇🏽, RT, share your 💬 & expertise with us Support by edu grants AbbVie JanssenUS Takeda

#MondayNightIBD Stefan Holubar MD MS GutlessandGlamorous Nigel H 🎸🎸🎸🎸🥁 Danielle Marie Vitelli O’Connor About IBD: Amber-Writer, Journalist, Podcast Host Lori Plung Tina Aswani-Omprakash, MPH Brooke Abbott Abron aka The Crazy Creole Mommy Natalie Hayden ⭐️Megan E. Riehl, PsyD⭐️ #IBDAlgo #MondayNightIBD Aline Charabaty, MD, FACG, AGAF @josephHabibi_MD 🎯#IPAA vs #Ostomy considerations in adults w UC Stefan Holubar MD MS ✅Who is fit for IPAA vs who is not ✅What if pts decide to stop at the ileostomy stage? 🎯PostConvo #CME polls🗳️👇(Answers in #IBDAlgo😉) Dr Feza Remzi

#CGH4ALL There is lack of clear guidelines on safe endoscopy in patients on GLP-1RA. This new 🔖 in CGH attempts to bridge the gap in 📚 🔗doi.org/10.1016/j.cgh.… Summary by Nishant Aggarwal, MD Stephen Firkins, MD Joy Yates, DO Neehal Shukla, MD Rajat Garg John Vargo Anthony Lembo, MD

Cold vs Hot Snare Resection Cold for: ▪️Everything ≤10 mm (even 0-Ip) ▪️SSLs of any size ▪️Flat adenomas (G-LST) 10-20 mm ▪️ Flat adenomas (G-LST) > 20 mm 🙏 Douglas K. Rex, MD #DDW2025

Endoscopy through stoma ▪️Use gastroscope for ileoscopy ▪️Use peds scope for colostomy ▪️Review stoma 1st ▪️Check for stenosis, prolapse, fistula ▪️Photo-doc peristomal findings ▪️Advance scope ≥10 cm past fascia ▪️Identify loop vs end ostomy ▪️Mucous fistula may be present

Arooj Mian #MondayNightIBD Aline Charabaty, MD, FACG, AGAF Joseph Sleiman, MD, FACP Jason Hou Y-ECCO Crohn's & Colitis Foundation Tauseef Ali MD, FACG AGAF FACP Katie Dunleavy Romy Chamoun, MD Jami Kinnucan, MD, FACG, AGAF, FCCF Florian Rieder Sanjeevani Tomar, MD Seb Raymond Cross Girls With Guts Shannon Chang, MD Mariam Naveed, MD Miguel Regueiro Bincy Abraham, MD, MS David T. Rubin, MD Jalpa Devi Dheera Grover SAIA Jordan Axelrad, MD, MPH Christina Ha MD Jennifer Seminerio Patriciakaazan Daniyal Raza, MD Madhura Balasubramaniam Sumit Bhatia Susan Kais, MD Mazen Almasry, MD David Faleck Marcel Yibirin, MD, MPH Samiksha Pandey, MD, MSc Shrinivas Bishu David Fudman, MD Robert Battat MD Hira hanif Abdul Sattar Shariq Mohammed Vipul Jairath MBChB DPhil Nutritional Therapy for IBD YOGI_IBD Amanda Johnson, MD Meena Bewtra Nisha Loganantharaj Lumír Kunovský Keith Siau Hannah Fiske Goodrich, MD 7/ 🔹Differentiate IDA vs ACD (📷👇) ⚠️Remember Ferritin increases during IBD🔥 🔹IDA in IBD: if Ferritin <30 ug/L & no inflam or <100 if 🔥 🧪 Ferritin >100 & TSAT <20% ➡️ACD 🧪 Ferritin 30-100 & TSAT <20% ➡️ IDA + ACD #MondayNightIBD #Back2Basics

#CGH4ALL Do we approach patients with elderly onset IBD differently? Are the outcomes different in these patients? 🎩 Tip to the authors of this new CGH paper. 🔗doi.org/10.1016/j.cgh.… Summary by Nishant Aggarwal, MD Tania Hviid Bisgaard Tine Jess @Dcharabaty Anita Afzali MD, MPH, MHCM, FACG, AGAF Miguel Regueiro