Delighted to share this paper in Nature Medicine in collaboration with NTU Singapore Integration of bacterial, fungal and viral data captures the complexity of bronchiectasis exacerbations Congratulations Micheál Mac Aogáin @KeirHolly nature.com/articles/s4159…

Analysis of microbial communities in the airways of patients with #bronchiectasis shows that interaction networks, rather than the relative abundance of individual species, are associated with exacerbation risk.Jayanth Kumar Narayana Micheál Mac Aogáin LKCMedicine nature.com/articles/s4159…

happy to see that our lionessR package is being used to answer new questions in biology! here, it was used together with generalized boosted linear models in an integrative microbiomics approach to study respiratory infections: nature.com/articles/s4159…

New paper from our lab, led by Jennifer Baker: Whole lung tissue is the preferred sampling method for amplicon-based characterization of murine lung microbiota Bottom line: for studying lung microbiota in mice, lung tissue >>> lavage fluid. microbiomejournal.biomedcentral.com/articles/10.11…

First paper from my PhD research out this week 🙌, UM Internal Medicine Research Symposium today 💙🩺💛, and #ATS2021 coming up fast 🫁🦠 - hmu if you want to talk microbes & mouse lungs, I'll be comm-ing my sci all. month. long.

High frequency of allergic-bronchopulmonary aspergillosis in bronchiectasis-COPD overlap New in CHEST Micheál Mac Aogáin @KeirHolly NTU Singapore University of Dundee journal.chestnet.org/article/S0012-…

Crystal clear exposé on similarity network fusion (SNF) for integrative analysis in respiratory medicine by Jayanth Kumar Narayana 👏👏👏 ERS publications Krasimira Tsaneva

Highlighted in the #ERScongress @EurrespirSoc state of the art Microbiome in bronchiectasis made a major leap forward in 2021 with papers in The Lancet Respiratory Medicine and Nature Medicine showing the key role of microbial diversity and Pseudomonas, and interactions between microbiomes

Great to see our editorial out with ⁦Darius Armstrong-James⁩ & S Chotirmall on ⁦Springer Nature⁩ special issue on Respiratory Mycoses: A Call to Action to Recognize, Educate and Invest. A hugely important area moving forward #fungi #respiratory link.springer.com/article/10.100…

#LKCMedicine A/Prof Sanjay Chotirmall & team discovered that the Neisseria bacteria living in our bodies is not as harmless as we thought & can cause infections in patients with bronchiectasis, asthma, and COPD. Read more bit.ly/3Bff1FT and bit.ly/3xpi51c.

Yet another important output from the Cohort of Asian and Matched European Bronchiectasis #CAMEB study. #Bronchiectasis #microbiome LKCMedicine

A lung pathobiont story: Thinking outside the Koch’s postulate box. Leopoldo Segal & Singh highlight work showing that Neisseria spp., viewed as commensals, can play a pathogenic role in bronchiectasis. cell.com/cell-host-micr…

Some thoughts on therapeutically targeting the respiratory #microbiome. Published recently with Leopoldo Segal and Chotirmall labs Jayanth Kumar Narayana #worldbronchiectasisday2024 #COPD #NTM tandfonline.com/doi/full/10.10…

Hard to believe i am saying this but our EMBARC European Bronchiectasis Consortium as 6 papers in this months AJRCCM! atsjournals.org/doi/full/10.11… atsjournals.org/doi/full/10.11… atsjournals.org/doi/full/10.11… atsjournals.org/doi/full/10.11… atsjournals.org/doi/full/10.11… atsjournals.org/doi/full/10.11…

Online today for World Bronchiectasis Day! The precision medicine era of bronchiectasis Great collaboration with my friend and colleague Sanjay Chotirmall outlining the history, and future pipeline for bronchiectasis and why personalized medicine is key atsjournals.org/doi/full/10.11…

As part of the World Bronchiectasis Conference 2024 ERS publications the European Respiratory Review publishes a series dedicated to bronchiectasis. err.ersjournals.com/content/33/173… Renata Riha Emma Johnson Merete Long EMBARC

In diagnostic labs, pre-analytical quality is everything. Why should microbiome research be any different? Research: respiratory-research.biomedcentral.com/articles/10.11…… Commentary: respiratory-research.biomedcentral.com/articles/10.11…… Respiratory Medicine Portfolio BMC #asthma #microbiome

Sputum metagenomics in bronchiectasis reveals pan-European variation: an EMBARC-BRIDGE study publications.ersnet.org/content/erj/ea… New study ERS publications on sputum metagenomics in bronchiectasis published by LKCMedicine researchers Kai Xian Thng and colleagues from LKCMedicine