They cracked a 20 year-old NLR biology puzzle. I think they deserve to celebrate 🙌 🥳 🍾

You can read more about it here kamounlab.medium.com/papers-galore-…

The plant immune system: From discovery to deployment: Cell

a must read piece by ⁦Jonathan D G Jones⁩ ⁦Brian Staskawicz⁩ & Jeff Dangl cell.com/cell/fulltext/…

Sam Altman 4月24日斯坦福闭门分享

🔥Introducing Llama3-8B-Chinese-Chat, the 1st llama3 model finetuned on English-Chinese datasets via ORPO.
🚀Our model consistently produces better responses for Chinese prompts than the Llama-3-8B-Insturct, and excels in logic, coding, math, and writing.

huggingface.co/shenzhi-wang/L…

Exciting news for the Python Single-Cell Community!
Save the date for the first scverse conference in Munich from September 10-12. Inspiring talks, interactive workshops, and networking opportunities. Stay tuned for the registrations, speaker announcements, and more! #scverse2024

github.com/sqjin/CellChat…

this is how statisticians computed linear regressions prior to the invention of the computer:

Single Cell Genomics Day starts tomorrow at 10AM ET!

Come for the awesome keynotes (Jason Buenrostro , Xiaowei Zhuang, IdoAmitLab) and to learn about our favorite new methods and trends for the field in the last year. All talks streamed on Youtube and satijalab.org/scgd

Are you applying RNA-seq or TraDIS/Tn-seq to antibiotic-treated bacteria? Check out our new preprint where Geraldine Sullivan, a Helmholtz Information & Data Science Academy HIDA visiting researcher, developed a method to fix biases introduced by interference with DNA replication. Thread 1/n biorxiv.org/content/10.110…

Want to hear about the latest updates/new techniques in single cell and spatial genomics? Check out the full agenda for our Single Cell Genomics Day on Friday, 3/29. All talks will be live-streamed (no registration required) at satijalab.org/scgd

All my favorite tools are agnostic or have bindings.

I love the fact I can pick up Quarto 📃, Arrow 🏹, Polars 🐻‍❄️ & switch between R, Python, & Julia with no issues.

Chaining open source libraries has never been easier.

There was a discrepancy in the log2 fold changes for marker gene detection between Seurat and Scanpy. New blog post: Do you really understand log2Fold change in single-cell RNAseq data? buff.ly/3TpQmZz

A comparison of marker gene selection methods for single-cell RNA sequencing data

👉59 methods + 14 real and 170 simulated scRNA-seq datasets
👉results highlight the efficacy of simple methods - Wilcoxon test, Student’s t-test and logistic regression

genomebiology.biomedcentral.com/articles/10.11…

bots working on all gears to figure out reliable colony PCR

NFTest: Automated testing of nextflow pipelines. Nextflow #PipelineTesting #Bioinformatics
academic.oup.com/bioinformatics…

Introducing Complete HeartX by Elsevier! 🚀

Dive into the heart with photo-realistic 3D models on Apple Vision Pro. Perfect for medical students & health pros. Explore anatomy, conditions like Myocardial Infarction & more.

A new reality in learning!

#CompleteHeartX

Want to hear about the latest updates/new techniques in single cell and spatial genomics? Check out my lab's eighth annual Single Cell Genomics Day on March 29. Keynotes from IdoAmitLab Jason Buenrostro and Xiaowei Zhuang. Please RT/spread the word! satijalab.org/scgd

Sugar coordinates plant defense signaling science.org/doi/10.1126/sc…

edgeR and limma are basically the only reasons I have R installed. Glad to see it’s maintained, updated and improved.
biorxiv.org/content/10.110…

Bioengineering a plant NLR immune receptor with a robust binding interface towards a conserved fungal pathogen effector dlvr.it/T1nRRs