NCI-supported researchers have found that incorporating genetic changes that cancerous cells use to stay alive into T-cell therapies may make the therapies better cancer killers. spr.ly/6010wUZSK #CARTcells #Immunotherapy

Access to new medicines in Canada, Europe, and the United States: Study finds less availability and longer waits for Canadian patients
👉🇨🇦lags far behind🇺🇸&🇪🇺
👉Clear demands to improve access to innovative therapies
CADTH Health Canada and PHAC: read carefully!👇…

Thank you Chicago Today for highlighting the importance of organ donation #livingdonor United Network for Organ Sharing (UNOS) Donate Life America UChicago Medicine nbcchicago.com/entertainment/…

Great flash talk on #cholangiocarcinoma #ACT #Tcells by Francie Bennett (Jenkins) Paulos Lab Emory Surgery Winship Cancer Institute of Emory University Emory Gastroenterology and Hepatology Fellowship at Emory Digestive Diseases Initiative Symposium

Priming agents transiently reduce the clearance of cell-free DNA to improve liquid biopsies
Science Magazine
doi.org/10.1126/scienc…
👉liver resident macrophages limit half-life of cfDNA
👉nanoparticles🚫clearance
😅Really cool & could help to boost sensitivity of ctDNA…

Not on the Twitter/X (that I know of) but started with key work by Parisa Malekzadeh #surgeonscientist and Drew Deniger. Building a TCR library that we can (hopefully) apply to so many people with advanced cancer!

Lisa Newman, MD MPH Mary Beckerle AACR AdvocateCollaborative (ACE) NCCS - National Coalition for Cancer Survivorship ASCO OncoAlert 'Feedback sandwiches' ~ Dr. Bianca Islam, MD, PhD, MSc (she/her) sharing leading practices & knowledge nuggets around communicating with patients & advocates.
* Trust doesn't happen on the 1st visit
* Involve advocates in research
* Meet people where they are at
* it's not a one and done thing
#AACR24

Excellent news for #CCA patients with high expression and/or amplified #HER2

In case you needed any more data on the value of exercise June M. Chan sharing that cancer-related pathways down regulated in men engaging in more vigorous exercise #AACR24 #AACR2024

'I want the minimum treatment for maximum benefit.' ~Manju George MVSc PhD Rectal Cancer Survivor, when asked for her response to data presented by speakers on overtreatment, need for biomarkers to predict treatment response, and trial design that help us find these answers. #AACR24

New AACR President Patricia M. LoRusso Dr. LoRusso gets right to the heart of things, 'I have a feeling many of you are here because of the recent cuts to the NIH budget.'
BINGO! At the same time, advocacy is used to doing amazing things with very little money so... it's possible #AACR24

Zanidatamab, a novel drug to treat certain patients with biliary tract #cancer , has been submitted to the #FDA via a Biologics License Application.

Read more here: curetoday.com/view/zanidatam…

Our next #Summit4CISpeakerSeries is on Earth Day! We'll be joined by #BioCanRx network researcher Dr. Rebecca Auer Rebecca Auer, MD & lab manager Carol Dore - both of the The Ottawa Hospital to learn about reducing carbon footprint in research labs. Join us! Register: bit.ly/3Tle4VD

NEW Study of 4.2K mets from 26 tissue types to eval composition, evolution, & relevance of #microbiome . Many insights: organ-specific tropism, microbial diversity & TILs, Fusobacterium & #ImmunoOnc in #lcsm . CNS tumors stand out (Fig 2B) 👀 #btsm #AACR24
cell.com/cell/pdf/S0092…

📣 Attending #AACR24 in San Diego, CA? Come find us at Booth AP8! Learn about the latest advancements in #cholangiocarcinoma research and grab some exclusive resources. We can't wait to meet you.

Dr. Steven Rosenberg delivered a terrific lecture today in acceptance of the AACR Award for Lifetime Achievement in Cancer Research. So well deserved and a testament to his remarkable career—congratulations! #AACR24 NCI Center for Cancer Research Surgery Branch spr.ly/6010wPZbC

Great listening to patty spears at AACR discussing the intersection of patient advocacy and community outreach and engagement programs at NCI-Designated Cancer Centers in their efforts to improve treatments and outcomes for all patients. #AACR24 #ASCRSSP

Check out this #AACR24 poster by first author, Johns Hopkins Medicine 3rd yr med student, Justin Huang. He’s thinking about how to extend benefits of immune checkpoint inhibition to pts w/ immunologically-cold tumors. 👏 👏, Justin! #OncTwitter #lcsm #RadOnc #ImmunoOnc #OncoAlert

Great summary on combined HCC- cholangiocarcinoma by my dear friend Udhayvir Grewal

🗓️ Join our Webinar: 'Investigational Treatment for KRAS-Mutated CCA-An Unmet Need' on April 11th, @ 4:00pm ET. There are currently no approved therapies for patients with KRAS-mutated CCA. Learn about a Phase 1b/2a study and its potential treatment. curecca.link/april11th.