Breaking News: Dr. Ruth Gottesman, a former professor, has donated $1 billion to a Bronx medical school, the Albert Einstein College of Medicine, with instructions that the gift be used to cover tuition for all students going forward. nyti.ms/49t5Zoq

Startups probe hidden viruses in the ‘dark genome’ to treat disease - read: the industry wakes up nature.com/articles/s4158…

Happy to share an analysis pipeline that is developed in our group led by resident expert in the area Alexander Ferrena, PhD We have been using it for many projects and it saves a lot of time and guesswork when multi group comparisons are needed

Two new chapters from my free online book in human genetics out this weekend! These complete Part 3 of the book, on human population structure and history: 3.3: Inferring human prehistory from genetic data [this thread] 3.4: Ancient DNA [next thread] web.stanford.edu/group/pritchar…

Scientists have mapped the genome of the Greenland shark, which could offer clues to the animal’s extreme longevity. nyti.ms/4eAL7xX

Biggest medical discoveries of the week (🧵) 1/10 A complete map of the fruit fly brain - the biggest and most detailed to date 140,000 neurons, which connect through 55 million synapses to permit vision, movement, and memory formation (nature.com/articles/s4158…)

Happy 2025! I am wishing all of you and your families a very happy new year, and I am looking forward to more exciting genomic advances in this coming year!

1/Here’s an excellent article - published in the recent WIRED issue, by Nobel prize winner Jennifer Doudna about how AI & machine learning are amplifying the impact of CRISPR & Gene editing in all walks of life - medicine, agriculture, climate change & research landscape.🧵👇

Visualizing RNA in live cells using CRISPR Doudna Lab Nature Biotechnology nature.com/articles/s4158…

A two-and-a-half-year-old girl shows no signs of a rare genetic disorder, after becoming the first person to be treated for the motor-neuron condition while in the womb. go.nature.com/4i9BpEx

Thank you NIH funded basic science

Devastated to hear that many #NSFfunded REU programs have been cancelled. I am a scientist because of my REU summer. It gave me a chance to experience what it was like to be a researcher, and to show myself and others that I could do it!

How a brain with #Alzheimer look in the microscope? Neurons are dying, and I literally see holes in the tissue, like below. You can see microglia🟡, brain immune cells, accumulating where tissue disappears (hippocampus & entorhinal cortex). Additional markers: Astrocyte🟣, pTau🔵

Jennifer Lai Remmel was born with a rare mutation that causes stomach cancer. After watching her mother die from the disease — and after removing her own stomach with 115 sites of carcinoma — she decided to test her own embryos and heal her family's future. This is her story.

🚨 BREAKING: With NIH cuts leaving young researchers in limbo, CRI is stepping up - $2.5M for postdocs to keep #CancerResearch moving forward. Breakthroughs tomorrow depend on investing in young scientists today. Read more: bit.ly/4iEQNsJ #FundingScience

.Mark Cuban More recent data shows NIH-funded research contributed to 354 of 356 drugs (99.4%) approved from 2010–2019. Public funding is indispensable to the health and betterment of the American people—we must do a better job communicating this.

A powerful and personal editorial from Nobel laureate Ardem Patapoutian: "I owe America my success. Today, its scientific future is in danger." Please read and share. cnn.com/2025/04/09/hea…

In recognition of World Parkinson's Day, we're resharing a recent story from the Jaenisch lab. Researchers uncovered how microglia — a type of immune cell in the brain — are involved in the disease: wi.mit.edu/news/whitehead…

Our Single Cell Genomics Day - highlighting our favorite new sc/spatial methods - starts Friday at 10AM ET! The most common question we get: is this open to anyone? Yes! Talks are free and live-streamed (no registration required) on Youtube and satijalab.org/scgd

Barbara McClintock proposed – over 40 years ago – that transposable element activity could be a response to stress, and I think that we are still only beginning to understand how right she was.