Applications now open for a new Clinical Research Training Fellowship PhD to study stromal radiotherapy resistance using patient organoids and single-cell signalling UCL Cancer Institute Vivian Li CRUKCOLcentre The Francis Crick Institute Pls retweet! Details: colcc.ac.uk/2023-crtf-proj…

Excited to share our new pre-print: ‘Cancer-Associated Fibroblasts Regulate Patient-Derived Organoid Drug Responses’ led by Maria Ramos and Alex Tong in collab. with Krishnaswamy Lab. (1/13) biorxiv.org/content/10.110…

Proud to see Maria Ramos present her work with Alex Tong and Krishnaswamy Lab on stromal regulation of PDO drug responses CRUKCOLcentre Pre-print: biorxiv.org/content/10.110…

Very excited to share our new pre-print: ‘A Single-cell Perturbation Landscape of Colonic Stem Cell Polarisation’ led by Xiao Qin and @FerranC96. (1/11) biorxiv.org/content/10.110…

I never thought a blocked nebulizer would make me so happy… Oh and passing my PhD viva yesterday! Thanks to the Tape Lab for the best gift ever!

Trellis meetings today from the Chilean Patagonia! biorxiv.org/content/10.110…

Innocently finished my PhD thinking I was saying goodbye to the CyTOF but then I joined Bodenmiller lab ✌🏼

.Maria Ramos discusses her research incorporating #fibroblasts into patient-derived #organoids in our latest interview from @ELRIG_UK’s Drug Discovery conference >>> biotechniques.com/cell-and-tissu…

Very excited to share two papers published today in Cell describing stem cell plasticity in CRC. (1/22) cell.com/cell/fulltext/… cell.com/cell/fulltext/…

In the first paper led by Xiao Qin and @FerranC96 we describe ‘An Oncogenic Phenoscape of Colonic Stem Cell Polarisation’. (2/22) cell.com/cell/fulltext/…

In the second paper led by Maria Ramos and Alex Tong ‘Trellis Tree-based Analysis Reveals Stromal Regulation of Patient-Derived Organoid Drug Responses’ we explored how the proCSC to revCSC axis effects CRC therapy responses. (13/22) cell.com/cell/fulltext/…

Chemotherapy becomes less effective because healthy cells push bowel cancer cells to grow more slowly, according to two studies led by Dr Chris Tape UCL Cancer Institute UCL Faculty of Medical Sciences. Treatments that push cells back into their fast-growing state could improve outcomes ucl.ac.uk/news/2023/dec/…

Excited to have our article "Trellis tree-based analysis reveals stromal regulation of patient-derived organoid drug responses," out in Cell today!! Great collaboration with Chris Tape lead by Maria Ramos and Alex Tong! authors.elsevier.com/sd/article/S00…

Krishnaswamy Lab Cell Chris Tape Maria Ramos Optimal transport is incredibly useful in single-cell analysis, but how do you handle controls? Chris Tape already has a great thread on the biological impact, so in this thread I’ll focus on the ML and computational aspects. (1/n)

In the latest issue! Trellis tree-based analysis reveals stromal regulation of patient-derived organoid drug responses dlvr.it/SzyVqb

Check out this Cancer Research feature on our recent work on PDOs and Trellis with Chris Tape Alex Tong Maria Ramos ! aacrjournals.org/cancerres/arti…