Have you ever seen real-time footage of a tumor developing outside a living organism? We are thrilled to announce a new paradigm in ex vivo cancer modelling rdcu.be/dFD2v. Let’s have a quick look!

This explains A LOT

Last Signalling Alliance Seminar of the series coming up on May 2nd! Chris Tape will present his latest and greatest work on tumor microenvironment organoids and Savitski Lab will resent their latest work on stability proteomics. Don't miss it! Please register to attend.

Huge thanks to The Constance Travis Charitable Trust who helped us purchase a new Opentrons Flex robot UCL Cancer Institute. Excited to start automating our SPLiT-seq / SIGNAL-seq assays!

Incredible work from Gabriele Picco Garnett Lab showing the power of WRN inhibitors in MSI CRC (with long TA repeats).

One can imagine a future when WRNi and neo-adjuvant ICB combine to cure MSI CRC.

Great to see so much interest in Callum Nattress’ poster demonstrating ‘Multimodal γδT Cell Cytotoxicity Overcomes Cellular Therapy Immunomodulation’

#AACR24 | UCL Cancer Institute | UCL Great Ormond Street Institute of Child Health | Science and Innovation at Cancer Research UK | CRUKCOLcentre

Come join us in 6CF from 10:15 to discuss ‘Systematic Functional Approaches for Understanding and Targeting Cancer’!

#AACR24

What is the role of the TME in lung cancer evolution? We are excited to share our new TRACERx paper “Spatial Architecture of Myeloid and T Cells Orchestrates Immune Evasion and Clinical Outcome in Lung Cancer” at #AACR24 , out in Cancer Discovery today rb.gy/q484j9 Tweetorial👇

Excited to chair a session at #AACR24 on 'Systematic Functional Approaches to Understanding and Targeting Cancer'

We've got an amazing lineup of speakers ready to share their insights!
Alison M. Taylor Chris Tape Alice Berger

abstractsonline.com/pp8/#!/20272/s…

Very excited for #AACR24 in a few days!

I'll be discussing some of our recent work in Session AT6 - 'Systematic Functional Approaches for Understanding and Targeting Cancer' (Monday 8th April, Ballroom 6 CF)

abstractsonline.com/pp8/#!/20272/s…

One of the problems with working on plasticity is that the algorithms start inviting you to scam material science meetings

Great Yale Cancer Center podcast with Krishnaswamy Lab discussing our recent paper on single-cell CRC+CAF drug responses

overcast.fm/+LwUqx4AaU

yalecancercenter.org/news/cancer-an…

Very honoured to have received the CRUK 2024 Horizons Explorer Recognition Award for our p110 PI3K activator work with Roger Williams MRC Laboratory of Molecular Biology - Also what are the odds to have received the (p)110 cloakroom ticket too? Science and Innovation at Cancer Research UK Cancer Research Horizons UCL Cancer Institute bit.ly/4akaj9G

Prototype lab swag ready for field testing at #AACR24

How to link single-cell diversity and the emergence and maintenance of robust multicellular processes in developed tissues? 🤔

What can we learn about multicellular coordination in tissues from single-cell omics data?

Read about our view: arxiv.org/abs/2403.06753

This will be my first presentation as a force ghost

Great talk last night from Jahangir Sufi showing how they troubshot and perfected single cell barcoding of organoids for multiplex analyses.

James Opzoomer James Opzoomer 🧬 from Chris Tape lab showcases how SIGNAL-seq technique is used to study single cell transcriptome and intracellular signalling analysis of 3D cancer models at City of London Centre tumour microenvironment symposium.