Let’s play a little game. Let’s say that you’re the CSO at a cancer pharma company, and you have to choose a target to go after. Here’s a gene – high expression is associated with poor prognosis in brain cancer. Looks like a good candidate for an inhibitor right?

🔌⚡️Arran de l’oposició a línies d’alta tensió perquè ens arribi electricitat provinent d’Aragó, sumada a la creixent oposició a la implantació de parcs d’energia renovable a Catalunya, crec que és bon moment per posar dades a un problema pel qual se’ns va acabant el temps.👇

🎥 El mensaje de Toni Nadal sobre las lenguas en el congreso del PP: "Si hay un filólogo, el político no tiene por qué intervenir"

Pep Guardiola - accompanied by the children of Noel Gallagher and Liam Gallagher - wearing a classic retro #ManCity shirt at Heaton Park for Oasis’ return to Manchester tonight. 😎

Tourism means becoming a nation of unskilled landlords and servants. It is not a path to prosperity, but a cope for its absence. It will worsen, not fix, the problems of Southern Europe and, as they get poorer, other developed countries too. My new article in PALLADIUM Magazine:

Amb tot el respecte, jo no visc d’això. És un hobby i ho seguirà sent a no ser que passés a treballar directament pel club. Prefereixo créixer sent fidel a qui sóc que fer coses que no m’omplen. I mira que abans els feia en castellà i anglès per créixer més i curiosament, quan

El sector del porc és només el 4% del PIB, dóna valor a la terra de secà i Catalunya rural, no necessita subvencions de la PAC, importa aigua virtual i exporta productes de major valor i només necessita l'1,6% de l'aigua de conques internes. Tu amb 25 anys vius a la Diputació.

Published today, an important paper proposes a framework dividing total fertility rate into two component parts: TFR = Total Maternity Rate (TMR) x Children per Mother (CPM) This lens shows that virtually all recent declines in fertility were due to increasing childlessness. 🧵

Mistral Le Chat should get a widget. Make it a European replacement for both ChatGPT and Google. 🇪🇺

La política catalana s'ha vist sacsejada aquesta setmana per una enquesta publicada per La Vanguardia, i que confirma l'ascens astronòmic de l'extrema dreta a Catalunya. Si m'ho permeteu, us dono la meva opinió 🧵

Many people think of proteins as having a biological function — catalyze reactions, detect pathogens, etc. At a higher level, though, proteins are programmable materials. They are an advanced form of nanotechnology, made from templates that we can read and write and understand.

We are all so fucking lucky. We are the luckiest mfers in history. You can fly anywhere on Earth in less than 24 hours. Your great-grandfather died within 50 miles of his birthplace. You can talk to anyone alive from your pocket, for free. You can start a business from your

Does anyone have more of this genre of image of old and new cultures colliding

Crawling isn't innate (unlike walking). Every baby must *invent* crawling, from scratch, using extremely little data, and no reference to imitate. Which is why different babies end up with different ways of crawling. Sometimes people tell me, "you say AI isn't intelligent until

Adaptive persistence of elite families despite regime change, alongside lasting regional scarring, highlighting the role of cultural transmission for social mobility, from Carol H. Shiue and Wolfgang Keller nber.org/papers/w34451

Insisto: la política DECLARADA del gobierno central es el incremento del PIB mediante el aumento de la población vía flujos migratorios masivos. Sin embargo, ha decidido no asumir el coste de adaptar servicios públicos ni las infraestructuras, lo que genera un desajuste fiscal

In 1303, during a lull in the Reconquista, 6,500 unemployed Catalan mercenaries were hired by the Byzantines to check the advance of the Turks in Anatolia. This "Catalan Company" gained a series of victories over the Turks, driving them back in West Asia, buts so ravaged the

Immensely glad to see that De Gaulle is trending again in Europe! He is, bar none, the last European leader to truly get it. One thing to bear in mind though, because I'm seeing the mistake being made all the time: Gaullisme is a mindset and a set of principles, but how De

I'm so happy to finally see this part of my PhD out 🔬💃🎉 where we show the important role that ARID1A plays in regulating the tumor microenvironment! nature.com/articles/s4141… Núria Eritja IRBLleida IRBLleida-IDIBELL precision therapies

"Congrats! And this is just the beginning, many more to come! 🚀"