APOL1 Genotyping Is Incomplete without Testing for the Protective M1 Modifier p.N264K Variant

Recently, two papers have robustly and independently validated genetically the protective effect of the #APOL1 N264K missense variant against #FSGS and #CKD
Read about some of the…

Landmark in Transplantation👑

Genetically-edited pig kidney with 69 genomic edits successfully transplanted into a living patient!

Congrats to Dr. Riella, Dr. Kawai, Dr. Elias and the entire team!

Leonardo V. Riella

massgeneral.org/news/press-rel…

Recruiting at Yale Nephrology !

AMPK activation by Metformin in FSGS - a phase II trial. Our rationale and design paper is out at KIReports. Yale Nephrology F. Perry Wilson, MD MSCE John Cijiang He
kireports.org/article/S2468-…

Since first kidney transplant >50 years ago, little has changed in the approach to prevent rejection after transplant. Excited to share our work changing the paradigm by expanding Tregs& allowing immunosuppression reduction jci.org/articles/view/… View details 👇 Mass General Transplant

Congrats Naoka Murakami and Aravind Cherukuri PhD MRCP (UK) e you

Meeting Report by Cravedi et al, 'Advancing Mouse Models for Transplantation Research'

doi.org/10.1016/j.ajt.…

Very happy to have contributed to this work and seminar Yale Nephrology AST Community of Transplant Scientists

Reviewing is critical to the the health of science. Peer review is strained to near a tipping point. Rule of thumb, publish 1, review 3. Have reviewed >900 papers but I am a bit behind now. But quality comes first. Grateful to the cardiologists to honor a kidney doc. Circulation

Very nice summary of going from GWAS hit to mechanisms in NDT..
doi.org/10.1093/ndt/gf…

Multiomic profiling of #transplant #glomerulopathy reveals a novel T-cell dominant subclass

doi.org/10.1016/j.kint…

Erasmus MC Transplantation Institute RWTH Aachen Uniklinik RWTH AC LUMC Leiden Harvard Medical School MGH Pathology🔬

#OpenAccess #kidneytranplantation #kidneypath #PathTwitter #transcriptomics

Big congratulations SSC_Lab 🧬 and collaborators for these highly impactful findings nature.com/articles/s4146…

Congratulations to our just-matched fellowship class beginning in 2024! 🎉

We are already so excited to have you here with us next summer! 🫘🫘

Yale Internal Medicine #FellowshipMatch #MatchDay #Nephrology

A large-scale retrospective study enabled deep-learning based pathological assessment of frozen procurement #kidney #biopsies to predict graft loss and guide organ utilization.

doi.org/10.1016/j.kint…

Icahn School of Medicine at Mount Sinai #RenalPath #Transplantation Yale School of Medicine University of Sydney UZ Leuven

Wonderful study led by Weijia Zhang - should hopefully guide the use of frozen section results in procurement biopsies using AI-pathology. Glad to be a part of this dataset. Yale Nephrology Menon Lab

On November 02, 2023, Dr. Madhav Menon delivered a fascinating talk titled 'Recipient APOL1 Genotype Effects in Kidney Transplantation' at the ASN Kidney Week's APOL1 and Kidney Transplantation session! 🎉 Don't miss out on the groundbreaking insights shared! American Society of Nephrology #KidneyWk

Researchers develop improved method for measuring kidney structures in focal segmental glomerulosclerosis.

Learn more from Yale Nephrology.

Dennis Moledina, MD PhD F. Perry Wilson, MD MSCE Madhav
medicine.yale.edu/intmed/news-ar…

Since the discovery of variants in APOL1 and their link to kidney disease in those of recent African ancestry, a wide body of research has emerged. This Review examines the reports which placed the podocyte at the center of our understanding of APOL1-FSGS bit.ly/KID0216