Wondering about the appetite of infarct macrophages? Check this out! Smad3 Cranks Up the Appetite of Infarct Macrophages | Circulation Research ahajournals.org/doi/10.1161/CI…

Macrophages facilitate post myocardial infarction arrhythmias: roles of gap junction and KCa3.1 thno.org/v09p6396.htm #Theranostics This new manuscript confirms our observation that #macrophages couple electrically⚡️💕with cardiomyocytes cell.com/fulltext/S0092…

Macrophages mess with ❤️ rhythm ⚡️ transcriptomics and protein data describe 3-fold expansion of these leukocytes in patients with atrial fibrillation. Among the top expressed genes: osteopontin (SPP1), catalyzing atrial fibrosis and inflammation ❤️‍🔥 science.org/doi/10.1126/sc…

In the HOMER mouse, stopping macrophage recruitment (CCR2 KO) or deleting SPP1 reduced atrial fibrillation. 👇 Targeting recruited macrophages may reduce atrial remodeling and conduction heterogeneity in afib patients.

A big thank you to the amazing team, the collaborators, our funders, the editor and our reviewers for going on this journey with us! We put macrophages on the arrhythmia map! Kamila Naxerova Maarten Hulsmans @nih_nhlbi Maximilian J. Schloss Patrick Ellinor

Padam, padam. And I can tell that you're all in, cause I can hear your heart beatin' But only if you don't have too many recruited macrophages in there! Check out our new paper, a great collaboration with Matthias Nahrendorf's lab: science.org/doi/10.1126/sc… youtube.com/watch?v=p6Cnaz…

Macrophages are a key driver to atrial fibrillation, laying the foundation for a new therapeutic approach Elegant work in humans and mice deconvolute the pivotal role of these inflammatory cells science.org/doi/10.1126/sc… Science Magazine Maarten Hulsmans Matthias Nahrendorf Kamila Naxerova

You know what’s better than rocket science 🚀? ? Cardiac macrophages science 🫀!! New masterpiece from Maarten Hulsmans and the group deciphering the role of recruited macrophages in atrial fibrillation⚡️ science.org/doi/10.1126/sc… Matthias Nahrendorf Kamila Naxerova

This week in Science Magazine, Maarten Hulsmans, Maximilian J. Schloss, I-Hsiu Lee, Kamila Naxerova, Matthias Nahrendorf, & colleagues uncover a role for recruited CCR2+SPP1+ #macrophages in #AtrialFibrillation, the most common type of #heart #arrhythmia! bit.ly/Sci_abq3061

Another powerful study highlighting that macrophages are an untapped source of therapeutic targets with new data showing the role of macrophages atrial fibrillation science.org/doi/10.1126/sc…

After 5 years in the making, I am elated to share our work on how cardiac macrophages elicit atrial fibrillation Science Magazine. Specially proud of our surgical MR model. What a team we were with Matthias Nahrendorf & Maarten Hulsmans + entire lab MGH Center for Systems Biology science.org/doi/10.1126/sc…

It was an honor to participate in this project with you and your team. If atrial fibrillation is ever cured, it will have to be done at the molecular level and not by increasing the number of lesions or arguing about what energy source works best. Many thanks to Science Magazine

Recruited macrophages are culprits in atrial fibrillation dlvr.it/SsshRb

Research highlight on the recent study by Maarten Hulsmans, Maximilian J. Schloss et al. in Science Magazine showing that recruited #macrophages elicit #AtrialFibrillation| Kamila Naxerova, Patrick Ellinor, Matthias Nahrendorf | nature.com/articles/s4416… 👉rdcu.be/diZes