Grateful to share our work on placental senescence in PPCM and preeclampsia in Science Translational Medicine.
Thanks to my mentors Drs Jason Roh and Anthony Rosenzweig, MD, and all coauthors and collaborators. MGH Cardiovascular Research Center
Paper here: science.org/doi/10.1126/sc…

The care challenges during and after #cardiac_arrest resuscitation can be major. What to do with patients in refractory cardiac arrest; how to optimize post-arrest outcome. Read about it in this CCS Clinical Practice Update. Heart Rhythm Society European Society of Cardiology CriticalCare.news CritCareCardiol

.AHA Science: Paper describes the overlap in #HeartFailure etiologies and case definitions, highlights strategies to improve quality of evidence on related etiologies, and advances heart failure #registry science. Figure: sample registries in World Health Organization (WHO) regions. ahajournals.org/doi/10.1161/CI…

❤️Our April issue is out❤️ Discover the new online tool BulkECexplorer, find out how Histone H1.0 regulates #myofibroblast activation, learn about the effectiveness of GLP-1RA and #SGLT2i for cardiovascular risk reduction, and more!

nature.com/natcardiovascr…

Another cutting-edge application using #MINFLUX
More will follow soon.

Very interesting and thought provoking work || Identification of senescent, TREM2-expressing microglia in aging and Alzheimer’s disease model mouse brain | Nature Neuroscience nature.com/articles/s4159…

Excited to share our study showing that exercise helps heart health in part by acting through the brain. By strengthening the prefrontal cortex, exercise cuts stress signals…which cuts heart disease events. jacc.org/doi/10.1016/j.…

Research Highlight | Grune et al. in Circulation show that immune activation in acute respiratory distress syndrome (ARDS) induces shifts in #cardiacmacrophages like those observed in individuals with #COVID19 . nature.com/articles/s4416…

👉 rdcu.be/dEx91

#ChallengeTheDogma ! Prof. Hao Wu, Du, Healy, David &co show nature that gasdermin D #GSDMD (& other GSDMs) need ROS-dependent S-palmitoylation to form pyroptotic pores. S-palmitoylation of full length (non-cleaved 🤯) GSDMD drives pores & #pyroptosis ! doi.org/10.1038/s41586…

Following a rigorous international recruitment process, the University of Ottawa Heart Institute has named Dr. Katey Rayner as its next chief scientific officer and vice-president of research. Congratulations!
ow.ly/vue050Rcg9g Katey Rayner #ottnews

Can we harness #immunometabolism to promote atherosclerosis regression? Check out our findings in PNAS showing the role of the IRG1-itaconate axis in atherosclerosis Yannick Cyr Fazli Bozal. Thanks to our collaborators GiannarelliLab NYU CVRC PNASNews 🧵pnas.org/doi/10.1073/pn…

Chiara Giannarelli’s science/commitment to advancing the AHA mission embody the spirit of the Hoeg award created in memory of Dr. Hoeg. We are thrilled to announce her as our invited lecturer who will present a lecture of her choice during the Sat. Plenary @ #VascularDiscovery24 🔬

Circulation Research #Circadian Mechanisms in #Cardiovascular and #Cerebrovascular Disease Compendium Alert!

#Stroke in the Time of Circadian Medicine ahajrnls.org/3vpjwyD
Authored by Drs. P Mergenthaler, JS Balami, AA Neuhaus, and colleagues

Interested in studying how the brain controls our cardiovascular health? Come and join our growing lab at MGH and HMS as a PostDoc. Expect full support, scientific freedom, and a very friendly environment. Check here for details x.com/jobRxiv/status… Please RT!

Exactly four years after the first shutdown came into effect MGH Center for Systems Biology, I'm thrilled to see our paper on cardiovascular complications in viral ARDS published Circulation Thanks to Matthias Nahrendorf stands with Israel and everyone who supported this project ahajournals.org/doi/10.1161/CI…

Severe lung infection during COVID-19 can cause damage to the heart | NHLBI, NIH nhlbi.nih.gov/news/2024/seve…

A very balanced and scholarly commentary on the controversy around meningeal lymphatics and amyloid Aß clearance- nature.com/articles/s4416…
Nature Cardiovascular Research costantino iadecola Weill Cornell Medicine

Look forward to seeing you at 2024 cardiac regulatory mechanisms GRC!

#STED shows a new and unexpected facet of its capabilities: quick, effective and precise fluorophore tracking. #MINFLUX . Good work Henrik, Lukas, Michael, Mira...