Michael Alexanian (@m_alexanian) 's Twitter Profile
Michael Alexanian

@m_alexanian

Assistant Professor @GladstoneInst @UCSF studying Cardiovascular Epigenomics. Theater teacher @UCSF_Improv michaelalexanianlab.com

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calendar_today28-09-2013 14:12:29

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McKinsey Lab (@mckinseylab) 's Twitter Profile Photo

Thank you AJP-Heart and Circ for publishing our recent work on BRD4 in cardiac macrophages. Huge effect on MHC-II levels. doi.org/10.1152/ajphea…. Great team effort and collaboration with many, including Ron Vagnozzi and Michael Alexanian.

Thank you <a href="/ajpheartcirc/">AJP-Heart and Circ</a> for publishing our recent work on BRD4 in cardiac macrophages. Huge effect on MHC-II levels.  doi.org/10.1152/ajphea…. Great team effort and collaboration with many, including <a href="/VagnozziRJ/">Ron Vagnozzi</a> and <a href="/m_alexanian/">Michael Alexanian</a>.
Isha Jain (@ishahjain) 's Twitter Profile Photo

🚨 New paper alert! 🚨 Check out our latest work on HypoxyStat, a small-molecule therapy that increases oxygen-hemoglobin affinity and provides a practical form of hypoxia therapy. A great collaboration with Maze Therapeutics 🔗 Paper: doi.org/10.1016/j.cell… Cell

Benoit Bruneau (@benoitbruneau) 's Twitter Profile Photo

The latest from Gladstone Institutes of Cardiovascular Research and UC San Francisco: Isha Jain's lab, with an outstanding discovery of a small molecule that mimics hypoxia, to treat neurodegenerative diseases. The amazing Sylar Blume, RA in Isha's lab, is first author! cell.com/cell/fulltext/…

Eldad Tzahor (@tzahore) 's Twitter Profile Photo

Super excited to share that our manuscript is finally OUT @CellSystems!!🚨 Cold and hot fibrosis define clinically distinct cardiac pathologies. cell.com/cell-systems/f…🧵(1/)

Gladstone Institutes (@gladstoneinst) 's Twitter Profile Photo

Researchers at Gladstone develop a drug that mimics the cellular effects of low-oxygen therapy for the treatment of inherited mitochondrial diseases. Isha Jain Cell Arc Institute UC San Francisco Maze Therapeutics NIH CDMRP gladstone.org/news/daily-dru…

Benoit Bruneau (@benoitbruneau) 's Twitter Profile Photo

for #heart month, a nice piece on what we at Gladstone Institutes are doing to understand heart disease better. Featuring Michael Alexanian Theodoris Lab and Katie Pollard. for heart month, a nice little piece on what we do at Gladstone for the heart gladstone.org/news/matters-h…

Mahmoud Abdellatif (@mah_abdellatif) 's Twitter Profile Photo

4 y ago, we showed that boosting NAD+ treats exp. HFpEF. Now, I am thrilled to share our EHJ Editor-in-Chief paper, where we reveal this relies on autophagy activation via reduced IGF1 signaling (not deacetylation!) and translational relevance in a prospective cohort! academic.oup.com/eurheartj/adva…

Javid Moslehi (@cardiooncology) 's Twitter Profile Photo

The Moslehi laboratory is recruiting a post-doctoral fellow with a PhD in immunology or molecular biology. See below! nature.com/naturecareers/… Below information about the lab: cardiooncologylab.ucsf.edu Interested candidates can email me with CV! [email protected]

The Moslehi laboratory is recruiting a post-doctoral fellow with a PhD in immunology or molecular biology. 
See below!
nature.com/naturecareers/…
Below information about the lab:
cardiooncologylab.ucsf.edu
Interested candidates can email me with CV! 
javid.moslehi@ucsf.edu
Andrés Hidalgo (@andrshidalgo16) 's Twitter Profile Photo

I am saying goodbye as an active member of X (but find me in sandra rodriguez.bsky.social) with our exciting new paper nature. The fruit of massive work by Tommaso Vicanolo, Alaz and Jackson Li, and our superb collaborators Lai Guan NG and stefan uderhardt 🔬🧫💉📷. True teamwork! nature.com/articles/s4158…

Improv at UCSF (@ucsf_improv) 's Twitter Profile Photo

🎭 This Friday, March 28, our #UCSF #improv group is hitting the stage at The Lost Church San Francisco! A bunch of #scientists doing improv—what could go wrong? (Or very right 😄) Expect laughs, chaos, and a great show! 🎟️ Grab your tickets here: thelostchurch.my.salesforce-sites.com/ticket/patront…

🎭 This Friday, March 28, our #UCSF #improv group is hitting the stage at <a href="/TheLostChurchSF/">The Lost Church San Francisco</a>!
A bunch of #scientists doing improv—what could go wrong? (Or very right 😄)
Expect laughs, chaos, and a great show!
🎟️ Grab your tickets here:
thelostchurch.my.salesforce-sites.com/ticket/patront…
Dr. Kaia Mattioli (@kaia_mattioli) 's Twitter Profile Photo

our work on the molecular differences between transcription factor isoforms is out now in Molecular Cell! key point: 2/3rds of TF isos differ in important properties like DNA binding & transcriptional activity many are "negative regulators" that are misexpressed in cancer

our work on the molecular differences between transcription factor isoforms is out now in <a href="/MolecularCell/">Molecular Cell</a>!

key point: 2/3rds of TF isos differ in important properties like DNA binding &amp; transcriptional activity

many are "negative regulators" that are misexpressed in cancer
Michael Alexanian (@m_alexanian) 's Twitter Profile Photo

Still buzzing from this show — what a night! So lucky to share the stage with such a brilliant, hilarious crew. Thanks to everyone who came out! 💥🎭

Cathrine Sant (Petersen) (@cathrine_sant) 's Twitter Profile Photo

CHOIR is now online Nature Genetics! CHOIR is a new clustering method for single-cell data that evaluates whether clusters represent statistically distinct cell populations. CHOIR scales to millions of cells and works with single-/multi-omic data of any type! nature.com/articles/s4158…

McKinsey Lab (@mckinseylab) 's Twitter Profile Photo

Our first foray into using AI to tackle human cardiac fibrosis. ahajournals.org/doi/full/10.11…. Amazing collaboration with Gregory Way and waysciencelab.com. Spearheaded by Josh Travers and Jenna Tomkinson. Tip of the iceberg. Stay tuned!

Our first foray into using AI to tackle human cardiac fibrosis. ahajournals.org/doi/full/10.11…. Amazing collaboration with <a href="/gwaybio/">Gregory Way</a> and waysciencelab.com. Spearheaded by <a href="/JoshTravers89/">Josh Travers</a> and <a href="/jenna_tomkinson/">Jenna Tomkinson</a>. Tip of the iceberg. Stay tuned!
Isha Jain (@ishahjain) 's Twitter Profile Photo

🚨Preprint alert!🚨 Why do high-altitude populations have lower rates of metabolic syndrome and lower blood glucose? Superstar postdoc Yolanda tackled this❓tinyurl.com/2x7ptyn8 Gladstone Institutes Arc Institute UC San Francisco #hypoxia #oxygen

Junyue (@junyue_cao) 's Twitter Profile Photo

Thrilled to share our latest preprint led by the fantastic student Ziyu Ziyu Lu! We constructed a scATAC-seq atlas profiling > 500 mouse tissues to explore cell population dynamics during mammalian aging and the associated chromatin landscape changes: biorxiv.org/content/10.110…

Thrilled to share our latest preprint led by the fantastic student Ziyu <a href="/ziyu__lu/">Ziyu Lu</a>! We constructed a scATAC-seq atlas profiling &gt; 500 mouse tissues to explore cell population dynamics during mammalian aging and the associated chromatin landscape changes: biorxiv.org/content/10.110…
Johannes Backs (@johannesbacks) 's Twitter Profile Photo

Maarten van den Hoogenhof found a specific way to improve cardiac function in RBM20 cardiomyopathy. CAMK2 inhibition might become the first tailored therapy for a Dilated Cardiomyopathy (after mavacamten for Hypertrophic Cardiomyopathy): biorxiv.org/content/10.110…