❗️Excited to share my PhD work in Genome Biology: PRODE recovers essential and context-essential genes through neighborhood-informed scores. What is PRODE, and how does it help?👇

Michael Caplan and myself have put together a thorough review on #PKD. We worked for over a year with multiple calls, long discussions, writing and re-writing…intense and fun! Hope the outcome is appreciable, final version in prep pubmed.ncbi.nlm.nih.gov/39938884/

A study by the group of Marta Biagioli, featured on the cover of Molecular Therapy, explores how SINEUP-CHD8 molecules can modulate CHD8 protein levels, a key factor in neurodevelopmental disorders. 📖 Read more: cell.com/molecular-ther… #Neuroscience #Autism #RNA

How are chromosome breaks repaired and how is their repair influenced and facilitated by nuclear and genome dynamics? Fantastic initiative and collaboration with Karim Mekhail, Irene Chiolo, and Gaëlle Legube lab Chromatin Repair. Nature Reviews Molecular Cell Biology Link to article: rdcu.be/edViW

A CDK4-selective inhibitor puts the brakes on cancer cells dlvr.it/TJcFF9

We are accepting submissions for our upcoming special issue - Cilia and Flagella: from Basic Biology to Disease. This issue will be coordinated by two Guest Editors: Pleasantine Mill @Mill_lab and Lotte Pedersen Lotte Pedersen. journals.biologists.com/jcs/pages/cilia

Online Now: Small-molecule RNA therapeutics to target prostate cancer dlvr.it/TJgYlq

In L.A. heading to Ventura Beach for the #GRC on #mitochondria. Excited to share our long-standing work on mitochondria in #PKD and our more recent discovery of the cross-talk between #cilia and #mitochondria European Research Council (ERC)

I'm happy to share that I've joined IFOM as a Junior Group Leader, leading the Functional Genomics of Cancer Immunity Laboratory! 🔬 The lab investigates the links between DNA damage response (DDR) and cancer immunity. Exciting times are ahead—stay tuned!

From our curated list of cis variants affecting post-transcriptional & translational mRNA regulation, we focused on a C>T SNP in the 3'UTR of DDIT4. One letter, big impact. Huge thanks to all co-AU, particularly Alessandro Romanel, Laura Alunno & M. H. Hamadou. biorxiv.org/content/10.110…

Check out our review on "PLK4: Master Regulator of Centriole Duplication and Its Therapeutic Potential". Everything you need to know about centriole duplication, mitotic stopwatch and TRIM37-mediated cancer-specific vulnerabilities. Midori Ohta onlinelibrary.wiley.com/doi/10.1002/cm…

Sharing our latest work University of Zurich tracking DNA damage inheritance by Live+QIBC nature.com/articles/s4158…. Huge congrats to Andreas Panagopoulos, M. Stout and all co-authors for this tour de force! Beautifully summarized by Sarah Aitken and E. Reilly Nature News & Views nature.com/articles/d4158….

Excited to share our new preprint on bioRxiv! We show that USP28 mutations found in cancer block its interaction with 53BP1, disrupting p53 stabilization. Check out the full story... biorxiv.org/content/10.110…

Congrats Vincenza vigorito we are proud of you!

Delighted to share our latest work showing how cells that evade #senescence after CDK4/6 inhibition are primed to become aneuploid because of their increased size. Great work by super PhD student Aanchal Pareri biorxiv.org/content/10.110…

🚨 Hot off the press!!! Wanted to share this to celebrate the momentous achievement from the Giunta Lab and for the human centromere / genomics communities as a whole... more posts to come next week but for now, happy Fourth & happy reading ❤️🧬💻 science.org/doi/10.1126/sc…

Con l'emendamento Centemero al DL Fiscale un'importante misura per innescare investimenti in -PMI italiane quotate -PIR -Startup -Debito pubblico Giulio Centemero Alberto Bagnai Marco Osnato Saverio Congedo toni ricciardi Ci auspichiamo sostenuto da tutte le forze politiche!

Supported by renewed NIH funding, we are recruiting a postdoc! We are a developmental cell biology group, & we ❤️ centrosomes and RNA localization. To learn more about our research and team, visit leritlab.org Apply here: faculty-emory.icims.com/jobs/149999/po…

Save the date! March 2027 on beautiful lake Maggiore right outside #Milan, are you ready for #Cilia2027? 🥳 Stay tuned for more info!

New work from the lab: Identification of CNOT1-CCR4-NOT as a suppressor of 53BP1-p53-p21 signaling Cell Reports. Congratulations to first author Antonio Galarreta and to all co-authors. cell.com/cell-reports/f…. #Microscopy #RNAiScreen #Condensates