Join "Accelerating Single Cell and Spatial Discoveries" on Oct 12 at noon and hear from russell littman about SCING for gene regulatory network modeling of scRNAseq and spatial transcriptiomics data: eventregistration.illumina.com/mX9Rd1?refid=S…

I don't use the phrase "tour de force" lightly... but it is warranted for this preprint by Kimberly Siletti et al. that just dropped from the Sten Linnarsson lab. biorxiv.org/content/10.110…

Welcome to LA #ASHG2022! Don't forget to stop by and hear amazing research from UCLA_Computational Medicine David Geffen School of Medicine at UCLA trainees! Including Yi Ding @kangchenghou @bhattac_a_bt Ruthie Johnson Vidhya Venkateswaran Christa Caggiano Brunilda Balliu and many more. compmed.ucla.edu/news/computati…

Yi Ding (Yi Ding) #ASHG22: Polygenic scoring estimates genetic value by aggregating signal across many loci. Potential for polygenic scores has already been well established -- but so have the challenges, especially the low accuracy in non-European populations.

Words cannot describe how incredibly proud I am of Yi Ding for her plenary talk at #ASHG2022 discussing her recent work discussing individual-level PGS accuracy! Really important implications from this work.

Please feel free to join us on Dec 6 at 2pm for russell littman’s dissertation defense “Development and application of single cell multiomics methods for complex disease”, Boyer 159 or zoom: ucla.zoom.us/j/5379649967

Wonderful to see this Perspectives article in Nature Medicine, showing the impact the HCA is already having on medicine. nature.com/articles/s4159…

Our SCING method for gene regulatory network (GRN) modeling for scRNAseq and spatial transcriptomics is formally published. Congratulations to russell littman, Michael Cheng, Ning Wang, and Chao Peng Lab@UCLA. Hope this is useful for your research! cell.com/iscience/pdf/S…

Our new study is out in eLife - the journal: “Shared and distinct pathways and networks genetically linked to coronary artery disease between human and mouse” doi.org/10.7554/eLife.… Thanks to the team led by zeyneb kurt Montgomery Blencowe and collaborators Drs. Jake Lusis and Johan Björkegren!

What does a mentor advise a mentee to do on the weekends? I encourage my lab members to rest but it’s a bit hypocritical because when I was at their stage I worked on the days off (and still do, kind of..). Maybe the best thing is to just make sure there's no expectation to work.

Excited to share my #ICLR2025 paper, with JC Hütter and friends! Genetic perturbation screens allow biologists to manipulate and measure the genes in cells = discover causal relationships! BUT they are expensive to run, expensive to interpret. ... We use LLMs to help!

Good news. After 2 rounds of venetoclax, GO, + chemo, my daughter has had a complete response. No detectable signs of the tumor that had completely shut her eye, which she was dangerously close to losing. 🙏🏾 to the amazing team St. Jude & the community for helping us get here.