People with 2 copies of APOE4 have ~10X risk of Alzheimer's. Here's the discovery of a protective variant and learning how fibronectin 1 plays a role
link.springer.com/article/10.100…

In 5 years, what will the preferred therapies for #MASH look like? Rohit Loomba Cell Metabolism cell.com/cell-metabolis…

Our new Global Researcher Access Fund is in ResearchProfessionalNews today! Speaking to UK Biobank’s Dr Lauren Carson, Linda Nordling highlights how this fund aims to triple the number of researchers accessing UK Biobank data from less wealthy countries. Read it here shorturl.at/dfMO9

Interested in #metabolomic #GWAS with #ratios ?

Read these papers side-by-side:

A #GWAS of #warfarin enantiomers and metabolites:

frontiersin.org/journals/pharm…

A #GWAS with ratios of acetaminophen metabolites:

mdpi.com/2218-1989/12/6…

Was a great pleasure to contribute to this work by Guerrera Chiara and colleagues on plasma proteomics optimisation! …alproteomicsjournal.biomedcentral.com/articles/10.11…

Happy to see my latest paper with Olink Proteomics in UK Biobank out in the latest print edition of Cell Genomics :

Genetic associations with ratios between protein levels detect new pQTLs and reveal protein-protein interactions.

cell.com/cell-genomics/…

Ramadan Mubarak to all my Muslim friends, families and colleagues here in #Qatar and elsewhere.

Here some interesting reading on the #metabolomics of #Ramadan fasting ...

doi.org/10.1016/j.ajcn…

link.springer.com/article/10.118…

Nod to Karsten Suhre, WeillCornellQatar, et al’s research! Their recent article's listed in Nature Communications Editors’ Highlights. The section showcases the 50 best research papers recently published in an area. Thank you for using #Seertechnology in your incredible work!

go.nature.com/436qapY

Congratulations!

'An important landmark in investigations of fasting'
How 7-day water-only fasting led to changes in >1,000 proteins, much of which were dissociated from the average 12.5 lb weight loss Nature Metabolism
nature.com/articles/s4225…
nature.com/articles/s4225…

Online now! Systemic proteome adaptions to 7-day complete caloric restriction in humans dlvr.it/T3Vw3D

Russia: Good video of the size of the population that turned out for Alexey Navalny's funeral in Moscow, the largest public gathering since anti-Putin protests under Boris Nemtsov's leadership over a decade ago, before he too was assassinated by Putin.

#Fasting shaped human evolution and is practiced by billions of people for #health and #religious reasons, but what happens to our body beyond shifting energy sources?

What happens to our bodies in *7 days* w/o any food?

nature.com/articles/s4225…

Genetic associations with ratios between protein levels detect new pQT... sciencedirect.com/science/articl…

The #Proteograph offers a new method for #pQTL mapping and large proteogenomic studies as shown in Karsten Suhre's, Ph.D., WeillCornellQatar, study. Thank you Technology Networks for sharing our news, emphasizing the importance of #proteomics & #genomics collaborations.

technologynetworks.com/analysis/produ…

Check out Karsten Suhre's latest pQTL sumstats! The full list of #GWAS can be found in the 2nd table here tinyurl.com/2p886w3u (search in the box for 'Suhre'). Fully curated data for the publication will follow in ~2 weeks 🧬

Karsten Suhre Do you think that there is the potential for introduction of collider bias using such ratios?

See here for a long read:

biorxiv.org/content/10.110…

Sahir Rai Bhatnagar