Thank you to Benjamin Sun and Brad Gibson for including me into their latest review paper, just out in Molecular & Cellular Proteomics:

Promises and challenges of populational proteomics in health and disease

doi.org/10.1016/j.mcpr…

The graphic is based on metabolomix.com/a-table-of-all…

WeillCornellQatar public relations are great at spreading the word about our research to the Arab world ... non-native speakers can use OpenAI ChatGPT4o to learn what we work on, but you can of course also read our paper with Serafim Batzoglou Seer right here: nature.com/articles/s4146…

By linking genetic variants to protein expression, #pQTL becomes crucial in #proteogenomics . Karsten Suhre & WeillCornellQatar have developed a novel method for pQTL analysis using unbiased, mass spec-based proteomics & Seer’s #Proteograph workflow. We’re pleased to be working with your team.

WCM-Q researchers publish landmark study into proteins

WCM-Q Research Nature Medicine Khaled Machaca Karsten Suhre Cornell Research & Innovation Qatar Foundation Weill Cornell Medicine QNRF Seer
qatar-weill.cornell.edu/media-center/n…

Reminder: If you are going to analyze large scale #multiomics data, consider using ratios:

Genetic associations with ratios between protein levels detect new #pQTLs and reveal protein-protein interactions

This also work for #metabolomics !

sciencedirect.com/science/articl…

Here the latest #GWAS study with #T2D in Qatar Biobank, led by Omar Albagha from جامعة حمد بن خليفة :

Genome-wide association study and trans-ethnic meta-analysis identify novel susceptibility loci for type 2 #diabetes mellitus.

Reminder: If you are going to analyze large scale #multiomics data, consider using ratios:

Genetic associations with ratios between protein levels detect new #pQTLs and reveal protein-protein interactions

This also work for #metabolomics !

sciencedirect.com/science/articl…

Did you know that omentin associates with serum metabolite profiles indicating lower #diabetes risk? Here the latest from the KORA F4 Study. Helmholtz Munich | @HelmholtzMunich

drc.bmj.com/content/12/2/e…

drc.bmj.com/content/12/2/e…

Karsten Suhre Nightingale Health Weill Cornell Medicine WCM Englander Institute for Precision Medicine WeillCornellQatar Olivier Elemento Jan Krumsiek Nightingale Health & Weill Cornell Medicine set a transatlantic scientific synergy precedent. #GlobalHealthInnovation #PrecisionMedicine

#Qatar launches Precision Health Institute. Proud to know that some of our WeillCornellQatar alumni is contributing to this ground-breaking endeavor.

qatar-tribune.com/article/120488…

Just finished this very nice review on genetics of complex traits
Covers developments in the field over the past 125 years up to the most pressing challenges today
Next steps will require creative people from many fields & this is a great way to encourage that cross-fertilization

I just added an interesting #pQTL study from the #China Kadoorie Biobank using the Olink Proteomics platform:

medrxiv.org/content/10.110…

to the Table of #GWAS with #proteomics

metabolomix.com/a-table-of-all…

Looks like this paper did not get much attention on Twitter (yet).

People with 2 copies of APOE4 have ~10X risk of Alzheimer's. Here's the discovery of a protective variant and learning how fibronectin 1 plays a role
link.springer.com/article/10.100…

In 5 years, what will the preferred therapies for #MASH look like? Rohit Loomba Cell Metabolism cell.com/cell-metabolis…

Our new Global Researcher Access Fund is in ResearchProfessionalNews today! Speaking to UK Biobank’s Dr Lauren Carson, Linda Nordling highlights how this fund aims to triple the number of researchers accessing UK Biobank data from less wealthy countries. Read it here shorturl.at/dfMO9

Interested in #metabolomic #GWAS with #ratios ?

Read these papers side-by-side:

A #GWAS of #warfarin enantiomers and metabolites:

frontiersin.org/journals/pharm…

A #GWAS with ratios of acetaminophen metabolites:

mdpi.com/2218-1989/12/6…

Was a great pleasure to contribute to this work by Guerrera Chiara and colleagues on plasma proteomics optimisation! …alproteomicsjournal.biomedcentral.com/articles/10.11…

Happy to see my latest paper with Olink Proteomics in UK Biobank out in the latest print edition of Cell Genomics :

Genetic associations with ratios between protein levels detect new pQTLs and reveal protein-protein interactions.

cell.com/cell-genomics/…