I stand in awe.

Cool story from our lab, led by John Calise, showing how assembly of metabolic filaments is tuned by phosphoregulation. Out now in bioRxiv

Great talk! Thanks Tianyang Liu for sharing your awesome structure!

12 days of NatureStructMolBiol covers! In March kollman lab showed us fantastic world of symmetry. The work elucidated how PRPS1 filaments form from D3 symmetric hexamers, stabilising allosteric sites within the enzyme and promoting its activation.

The deadline for the CSHL 2024 Cryo-Electron Microscopy Course is Monday, January 15th! Click the link below to be apply today! Good Luck! meetings.cshl.edu/courses.aspx?c…

.John Calise et al. kollman lab University of Washington explore the impact of S477 phosphorylation on two IMPDH1 variants that play a key role in GTP synthesis in the retina. hubs.ly/Q02k9-WJ0 Rubén Martínez-Buey #StructuralBiology #CellSignaling

In JCellBiol, John Calise et al. kollman lab University of Washington explore the impact of S477 phosphorylation on two IMPDH1 variants that play a key role in GTP synthesis in the retina. hubs.la/Q02kbj2_0 Rubén Martínez-Buey #StructuralBiology #CellSignaling

⁦The New York Times⁩ spelling bee is the worst!

Please join us in congratulating our own John Scott, who was recently awarded ASPET's Julius Axelrod award in Pharmacology! Congratulations to John, and all of this year's ASPET award-winners, for this well-earned honor! aspet.org/aspet/meetings…

Delighted to see this wonderful study out in its final form. Congrats Tom and Kelli. Toxoplasma gondii actin filaments are tuned for rapid disassembly and turnover | Nature Communications nature.com/articles/s4146… #Toxoplasma UConn MCB

Lamenting about mechanistic details! Those of us who, for decades, worked on establishing the role of protein oligomerization in function were relegated as doing incremental science! Now that folks are visualizing these in CryoEM structures, the findings is considered WOW!

Kicking off the 2024 Cold Spring Harbor CryoEM course CSHL Courses! It’s going to be a grueling but amazing 2 weeks!

Learning how to process data using cisTEM and Relion at the cryoEM CSHL Courses ! Tim Grant

Matthijn Vos is evaluating student grids at the ⁦CSHL Courses⁩ cryo-em course. He is a tough judge - a lot of 0/10 grids! ⁦Lander Lab⁩ ⁦Jennifer Cash⁩

Final processing has begun! Which team will have the best map? We’ll know in 4 hours. ⁦CSHL Courses⁩ #cryoem ⁦Lander Lab⁩ ⁦Jennifer Cash⁩

Congrats to all the participants of the 2024 CSHL Courses cryoEM course, and special congrats to Team 3: Nancy Jaiswal, Denjoi, Edem Gavor, the winners of this year’s competition! We hope you all had a great time and share the knowledge you’ve gained with others!

I finished my 2024 CSHL Courses cryoEM course! Amazing course and great people that I highly recommend to everyone! Special thanks to our instructors Lander Lab Jennifer Cash kollman lab, Matthijin,TAs, and guest speakers. Hope to see all the participants soon in future!

Brad Webb, kollman lab and colleagues based at J. Heyrovsky Institute of Physical Chemistry CAS and WVUBiochemistry provide structural insights into the regulation of the gate-keeper glycolytic enzyme phosphofructokinase-1 nature.com/articles/s4146…

BREAKING NEWS The Royal Swedish Academy of Sciences has decided to award the 2024 #NobelPrize in Chemistry with one half to David Baker “for computational protein design” and the other half jointly to Demis Hassabis and John M. Jumper “for protein structure prediction.”

Congratulations to David Baker of UW Biochemistry and Institute for Protein Design for receiving The The Nobel Prize in chemistry for “for computational protein design.” #NobelPrize