APOE4 impairs myelination via cholesterol dysregulation in oligodendrocytes | Nature nature.com/articles/s4158…

1. I’m excited to share our new work, conducted with my amazing mentor and advisor Karl Deisseroth, on the synaptic basis of behavioral timescale plasticity. Online today Cell Press: cell.com/cell/fulltext/…

We looked at the proteomic diversity of 18 different synapse-types! Check out what we found in the preprint below 👇Big thanks to my co-authors from Erin schuman lab at MPI for Brain Research and Swiss National Science Foundation for support. #TeamMassSpec biorxiv.org/content/10.110…

Here’s a shout out to all the women & girls in #STEM. May you be free to pursue your curiosity & always feed supported to do so. 10 years ago we said “Science remains institutionally sexist…” Have things changed?#internationalwomenandgirlsinscienceday nature.com/nature/volumes…

Check out our latest paper in Science Magazine about the mechanism of #psychedelic-induced neuroplasticity. Fantastic collaboration between Institute for Psychedelics and Neurotherapeutics labs Olson Lab, Lin Tian, PhD, John Gray, as well as @MccorvyL! science.org/doi/10.1126/sc…

We are excited to share our new manuscript on Nature Neuroscience where we report the flexible bioelectronics capable of tracking neural activity from the same cells during the entire adult life of mice.nature.com/articles/s4159…

Thrilled to see our new paper out in Nature Biotechnology . Spatial-CITE-seq: spatially resolved co-indexing of transcriptome and epitopes for multi-omics sequencing. Big shoutout to Yang Liu, my former postdoc @YaleBME and now assistant professor of pathology and neurology Yale School of Medicine !

We’re excited to extend noninvasive optogenetics beyond the brain to address a nearly 150-year-old question in a new study out today nature: nature.com/articles/s4158… Work led by Brian Hsueh, myself, and Karl Deisseroth, with an amazing team in the D-lab and many others!

Really excited to share some of my PhD work Nature Neuroscience! This story was and will continue to be a rollercoaster of emotions. Big thanks to Martín Ávila YY zhang and our collaborators. Without their help none of this would have been possible.

A high-resolution transcriptomic and spatial atlas of cell types in the whole mouse brain biorxiv.org/cgi/content/sh… #biorxiv_neursci

We present #Zebrahub: a timecourse atlas of zebrafish embryonic development, combining #scRNAseq time-course data with #lightsheet live imaging. Explore our seq. and imaging datasets interactively at biorxiv.org/content/10.110… zebrahub.org 1/n

Spatial epigenome–transcriptome co-sequencing🤩🤩🤩Beyond excited to see it out today nature! Enjoyable collaboration between my lab @YaleBME @YaleSEAS Yale School of Medicine and GonçaloCasteloBranco of Karolinska Institutet. The most informative tool for spatial multi-omics!! nature.com/articles/s4158…

Last year 25 female biotech CEOs gathered for the first time. This year we’ve doubled to 50 (!) and I’m feeling so inspired after spending the weekend with this group of badass women who are redefining what it means to be a leader. This is what the future of biotech looks like👇

Congratulations to The Brain Prize winners of 2023: Professors Michael Greenberg, Christine Holt and Erin schuman. They have done pioneering work on molecular mechanisms of brain development and plasticity Read: lundbeckfonden.com/en/pioneering-… #TheBrainPrize #BrainPrize23 #neuroscience

We are excited to introduce Phospho-seq, our approach for profiling intracellular protein and cell signaling dynamics alongside additional molecular modalities in single cells! Check out @JBlairSci's preprint at biorxiv.org/content/10.110…

WOW! science.org/doi/10.1126/sc…

Doyeon Kim asked: how can we map all the synapses which got potentiated during a particular memory formation? i.e., what is the shape of a memory? biorxiv.org/content/10.110…

These are astonishing results in weight loss. 24.% weight loss at 48 weeks. Average loss of 58 pounds. Blows out of the water everything else we've seen so far. endpts.com/lillys-retatru…

3D MERFISH, a dream comes true thanks to Xiaowei Zhuang, Rongxin Fang, Ph.D. and collaborators

Nature research paper: Rewiring cancer drivers to activate apoptosis go.nature.com/3OcVgoX