🔍 Key takeaways on Hereditary Breast Cancer Syndromes, from the new ⭐️ISMPO Guidelines on Breast Cancer in the Young.✨ 📄 Published in the latest Ind J Med Ped Oncology 🖊️ Lead: Dr. Jyoti Bajpai and team 👉 Read full article: ijmpo.org/ejournals/topi… #bcsm #breastcancer

HER2 Rx options in #LungCancer: Part 2/2 w/ Isabel Preeshagul & Eric K. Singhi, MD!! We 🗣️ the current & quickly changing treatment landscape in this space. Full📢 🌟 cor2ed.com/lung-connect/p… 🌟 oncbrothers.com/her2-nsclc-202… 🌟Also on “Oncology Brothers” Podcast #lcsm #OncTwitter #MedTwitter

A simple move, a big impact: Giving IV magnesium before cisplatin cut kidney injury risk by 20%! Safe. Cheap. Available. JAMA Oncology OncoAlert Oncology Brothers LARVOL jamanetwork.com/journals/jamao…

Cancer-associated Cachexia is a lethal metabolic syndrome marked by systemic inflammation, CNS appetite dysregulation, & muscle/fat loss—better characterized with imaging. Prevalent in cancers like pancreatic/lung, it's linked to IL-6, GDF-15, & tumor-driven energy drain. Trials

Therapy for Diffuse Astrocytic and Oligodendroglial Tumors in Adults: ASCO-SNO Guideline Rapid Recommendation Update Clinical Insights ASCO doi.org/10.1200/JCO-25…

🚨 REMORA trial: Lenvatinib 💊 24mg OD showed 38% ORR 🚀 in advanced thymic carcinoma post-platinum chemo. SD in 57% ⚠️ Grade 3 HTN in 64% Promising 2nd-line option #ThymicCarcinoma #Lenvatinib The Lancet Oncology doi.org/10.1016/S1470-…

Dose-individualisation of fluoropyrimidines based on pre-treatment serum uracil levels - European Journal of Cancer ejcancer.com/article/S0959-…

Toxic neuropathies are not as easy as one may think. There is no other kind of neuropathy for which history and neurological examination are so crucial for the diagnosis, as no definitive diagnostic tests are available. In addition, it is important to review the medical records

amazing collective effort from the group.. congratulations 🎊 research which matters and changes practice on the ground.. enough evidence to indicate that OMCT backbone with immunotherapy must be studied in a frontline trial.. The ASCO Post Dr Amol Akhade LARVOL Praveen Kumar Marimuthu Ajoy Oommen John

Nice slide to show PIK3, AKT and mTOR inhibitors for MBC ESMO - Eur. Oncology #esmobreast25

rulebooks will be rewritten very soon 🔪 🫁 IASLC jto

A detailed review of VEGF signaling and targeting, future directions. Open access that too. doi.org/10.1038/s41392… Dr Akhil Santhosh Dr. Foxpaws Fauxpas Animesh Valame MD DNB Josh Thomas Georgy Ajoy Oommen John Praveen Kumar Marimuthu

✨ Practice-changing for gallbladder cancer? A randomized phase 3 trial from 🇮🇳 evaluated NACTRT vs NACT in locally advanced GBC (T3/T4, N1, liver infiltration). Results: ✂️ R0 resection: 51.6% (NACTRT) vs 29.7% (NACT) p=0.01 ⏳ Median OS: 21.8 vs 10.1 mo HR: 0.56 (95% CI

ELN 2024 Genetic Risk for Less-Intensive AML Therapy 🧬⚖️ (Blood. 2024 Nov;144(21):2173) Favorable 🟢: •NPM1 (with FLT3-ITDⁿᵉᵍ, NRASᵂᵗ, TP53ᵂᵗ) •IDH2 (FLT3-ITDⁿᵉᵍ) •IDH1 (TP53ᵂᵗ) •DDX41 mutation •Other favorable cytogenetic/molecular profiles (NRASᵂᵗ,

🚨 Just published in JCO Global Oncology 📢 Our phase III METRO-CHASE trial shows triple oral metronomic chemotherapy significantly improves survival in platinum-refractory. #HeadAndNeckCancer. 🔗 doi.org/10.1200/GO-25-… #oncology #cancerresearch

Randomized Phase III Trial of Ramucirumab Beyond Progression Plus Irinotecan in Patients With Ramucirumab-Refractory Advanced Gastric Cancer: RINDBeRG Trial Journal of Clinical Oncology ascopubs.org/doi/10.1200/JC…

Could we Omit POLE sequencing in Endometrial Cancer Molecular Algorithm & replace with ER/PR ? POLE mut requires sequencing & is expensive, IHC staining =simple quick & easy. Large subgroup of low risk pts (44 %) where POLE seq is not needed. Only 1.4% would benefit from POLE seq

🚨 CAST trial from Australia-New Zealand - A practise changing one! PTCY with CNI - A new SOC for MSD transplants. Anti-metabolites can “rest in peace”! Below is the comparisons between BMT CTN 1703, HOVON-96 and CAST study. #bmt NEJM

The NIA charged an 84 year old man, but forensics now show that evidence was planted on a priest. It doesn’t matter whether the priest was Hindu, Christian, Muslim or Sikh. An 84 year old who wasn’t given a straw. Remembering Fr Stan Swamy on his death anniv July 5. In Parliament

🏃‍♂️💥 Exercise boosts immunotherapy! New study shows exercise increases gut microbiota-derived formate, enhancing CD8+ T cell–mediated antitumor immunity via Nrf2. ⭐️Formate may be a new biomarker for better ICI response in melanoma. Cell Press OncoAlert #microbiome #cancer