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Celebrating a full year of exciting science at our annual Immunobiology department Department of Immunobiology at UNIL retreat today! With Broz Lab, Julia Esser-von Bieren, Alexis A. Jourdain, Fabio Martinon, RebsamenLab, Tacchini-Cottier Lab and more. Faculté de biologie et de médecine (inactif) EHL Hospitality Business School

Excited to announce that my first paper from the Alexis A. Jourdain is out! Check 👇 to learn more about #Deadseq! Stay tuned for more😁

Thrilled to share our paper on #uridine catabolism! We found that both #uridine and #RNA can be used as energy-sources and fuel cell proliferation in glucose-limiting conditions. Many thanks to Alexis A. Jourdain for the opportunity to contribute to this fascinating project!

🚨PhD position opening in our lab at the Department of Immunobiology (DIB) in Lausanne! We are searching for a curious and motivated PhD student to study #innateimmunity, #inflammasomes or #NINJ1-induced cell death. For details: tinyurl.com/PBDIB Please RT and/or apply!

Do you want to learn how to isolate highly pure #mitochondria? Check below our newest paper describing a two-step tag-free mitochondria isolation protocol!

In this special issue of Molecular Cell on #stress I share my experience finishing my postdoc, moving to another continent and opening my lab during the #COVID19 pandemic. #newPI Read also the other 5 testimonies. cell.com/molecular-cell… Faculté de biologie et de médecine (inactif)

Do you want to learn more about nucleoside catabolism and its potential roles in energy metabolism, cancer and immunity? Check below ⬇️ the latest Opinion article in Trends in Endocrinology & Metabolism by the Alexis A. Jourdain

Online Now: Nucleosides are overlooked fuels in central carbon metabolism dlvr.it/T3WJG6 #trends #endocrinology #metabolism

Check the newest preprint from the lab in bioRxiv! Here Mads Foged and colleagues describe an exciting link between cytosolic translation and mitochondria RNA processing. Take a look at the thread and video below⬇️⬇️⬇️

We wrote a short Spotlight article Trends in Biochemical Sciences highlighting the recent work from Kim, Tan, et al. on mitochondrial RNA #methylation, #dsRNA degradation and #innate_immunity published Molecular Cell. By E. Recazens. Have a look 👀 sciencedirect.com/science/articl…

Available online - the Spotlight "Cytosine methylation flags mitochondrial RNA for degradation" from Emeline Recazens and Alexis Alexis A. Jourdain. #RNAdegradation #nucleicacidsensing #immunity authors.elsevier.com/sd/article/S09…

Incredibly honored to see our work on #uridine metabolism featured in the Cancer Metabolism 2.0 collection Springer Nature , next to work from Lyssiotis Lab and Anguraj Sadanandam ! Owen Skinner Joan Blanco-Fernandez Vamsi Mootha nature.com/collections/dj…

New preprint from the Alexis A. Jourdain lead by our amazing postdoc Miriam Lisci! Check it below to learn more about new mechanisms for cell survival under glutamine scarcity👇👇

Our story on a novel pathway that controls #mitochondria from the 𝐜𝐲𝐭𝐨𝐬𝐨𝐥 and influences #immunity is now peer-reviewed and available at PNASNews! pnas.org/doi/10.1073/pn… By M. Foged Department of Immunobiology at UNIL Faculté de biologie et de médecine (inactif) Christian Münch Vamsi Mootha #N6AMT1 #mtDNA #RNA_processing A recap 🧵

Stressed mitochondrial RNA granules from our recent work on the cover of PNASNews! A photo by E. Recazens illustrating our new story led by M. Foged on the cytosolic control of mitochondrial RNA processing and innate immunity by #N6AMT1. #mitochondria #dsRNA Faculté de biologie et de médecine (inactif)

📢We're recruiting📢 Our lab at the University of Lausanne is looking for a postdoctoral associate to study #nucleotide metabolism in physiology and cancer in vivo! #uridine #cancermetabolism #immunometabolism Faculté de biologie et de médecine (inactif) Faculté de biologie et de médecine (inactif) Department of Immunobiology at UNIL 🔗(PDF): jourdainlab.org/wp-content/upl…

Stoked to share TWO preprints on mitochondrial pearling! 🎉 We uncover how spontaneous #mitochondria pearling drives #mtDNA nucleoid distribution (doi.org/10.1101/2024.1…), and Gabriel (Gav) Sturm et al. dissect the biophysics behind it (doi.org/10.1101/2024.1…). Details below! 🔬🧵

📢We're recruiting📢 Our lab at the University of Lausanne is looking for a postdoctoral associate to study #nucleotide metabolism in physiology and cancer in vivo! Please share #uridine #cancermetabolism #immunometabolism Faculté de biologie et de médecine (inactif) Université de Lausanne 🔗(PDF): jourdainlab.org/wp-content/upl…

2 weeks left to apply to the postdoc position in our lab AND we are extending the call to 2 topics! ➡️ nucleotide metabolism in #immunometabolism and #cancer in vivo ➡️ mitochondrial RNA granules in #innate_immunity Same link: jourdainlab.org/wp-content/upl… Faculté de biologie et de médecine (inactif) mitojobs

🔔 Check below the latest prepint of the Alexis A. Jourdain about nucleotide metabolism led by Abigail Strefeler! ⬇️