Our #FeaturedProtocol this week: #Lightsheet fluorescence #microscopy to analyse the spatial distribution of #immunecells in the #tissuemicroenvironment bit.ly/47EYkln Fan Lab Penn Medicine Penn Medicine - Abramson Cancer Center Penn Radiation Oncology Residency PennCVI NAVBO

I'm looking for an intern! 🐣 If you just finished your master or are about to and want to do a 6 months+ project working with #organoids, #optogenetics, #singlecell and #spatial omics, DM or drop an email in the next couple of weeks

Cells can switch phenotype states, but we've long wondered what triggers that switch. In @mrndhntr's new paper, she shows that the mechanical microenvironment governs this type of plasticity in #melanoma: biorxiv.org/content/10.110…

Join us on Friday, 3/29! We will let you know more about Open-ST 😉

Beautiful new work from Nikolaus Rajewsky lab on DIY high-resolution and 3D spatial transcriptomics. Learn more at rajewsky-lab.github.io/openst/latest/

How do cell states contribute to the aberrant homeostasis of a tumor tissue? We propose a functional classification as Drivers, Passengers, and Trailers⁦⁩. Fun Xmas project w/ Michela & Chris ⁦MarineLab.🙏 ⁦Elizabeth McKenna⁩ & ⁦Cancer Discovery⁩! aacrjournals.org/cancerdiscover…

How to pick a problem. Today in Cell. 1/53 cell.com/cell/fulltext/…

1/8 We are hiring!!! 🐣🐣🐣 Fully funded PhD position in my group!

We would like to thank everybody who showed up yesterday to the talks of @tmpentimalli.bsky.social and Daniel León-Periñán for this meeting of Berlin Bioinformatics Social Group, this was a long one and we discussed 3D Spatial Omics in great depth! MDC-BIMSB MPI for Molecular Genetics CompBioBerlin

Our #OpenST paper is now online Cell! authors.elsevier.com/c/1jJckL7PXqR3U Very cool updates ahead🧵⬇️ Marie Schott Elena Splendiani #GiuseppeMacino Nikos Karaiskos Nikolaus Rajewsky

i am so excited about our open source inexpensive, sub-cellular capture, do-it-yourself Open-ST that transforms tissues into virtual tissue blocks in 3D - IDing pathways & gene programs driving phenotypes. a huge congratz to the team! cell.com/cell/abstract/…