Excited to share that I just started my lab at The University of Edinburgh on a Wellcome Career Development Award! Reach out if you’re interested in working on astrocyte subtypes & the glia limitans – we’re hiring!

Excited to share our new preprint describing a highly scalable #CRISPR screening platform based on neuronal activity. biorxiv.org/content/10.110… Read more below from Steven Boggess, who led this project:

An Imaging Specialist Position is open at the CALM microscopy core at UCSF Mission Bay! Please share this post! and apply if you are interested! aprecruit.ucsf.edu/JPF05024

Excited to share a BIG update from the Kampmann Lab to our previous preprint led by the fearless Bren, now a graduate student in the The Gu Lab at Harvard. We find that in inflammatory reactive astrocytes, mTOR-dependent endolysosomal remodeling leads to (1/3)

We have open positions for a postdoc and a research assistant in the beautiful city of Edinburgh at the UK Dementia Research Institute! Reach out if you want to know more about either of the positions!

Excited that we (@kampmannlab @asamelson1) could contribute to this work by Gan Lab (and collaborate with our former summer student Celeste): Human iPSC 4R tauopathy model uncovers modifiers of tau propagation cell.com/cell/fulltext/…

Today in cloning mischief: my ligation somehow snatched up a chunk of what appears to be the endogenous E. coli genome(?) instead of my intended insert. Science is super wild sometimes.

From Saturday’s earthquake in SF Alex Keip

Are you interested in in vivo #CRISPR screens in mice to uncover mechanisms of #neurodegeneration? 🐭🧬🧠 Apply for this SRA (technician) position in the UC San Francisco Kampmann Lab: sjobs.brassring.com/TGnewUI/Search… Great way to gain research experience before grad school! Please RT/share!

A suite of enhancer AAVs and transgenic mouse lines for genetic access to cortical cell types biorxiv.org/content/10.110…

CRISPR has the potential to cure many genetic diseases, but it’s notoriously hard to use in neurons. In this work we tackled 2 of the main hurdles: Cas9 delivery and DNA repair. And we discovered… The rules of genome editing are different in neurons👇🏾 biorxiv.org/content/10.110…

Very excited to see our manuscript on the Neurolipid Atlas online SJ Koppes - den Hertog @vanderkantLab @Martingiera! Big thanks to all collaborators! biorxiv.org/content/10.110… neurolipidatlas.nl A thread:

It's a day late, but for #FluorescenceFriday I've got some 🎇🎆 firework-shaped 🎇🎆 cortical mouse astrocytes (cell filled, sparsely labeled)

Fam: we are hiring (again!) this time for an NIH funded position ;) spread the word to join our growing team. careers.chop.edu/us/en/job/1010…

We are doing this again for the 2024-2025 UCSF Neuroscience Graduate Program Neuroscience Formal Seminar Series! Postdocs, apply to give a talk and get to know the UCSF Neuroscience community. Send CV and short abstract to [email protected]. Nominate yourself or others!

I'm so excited to share my first preprint from Pollen lab at UC San Francisco on the phylogenetic and spatial distribution of TAC3 interneurons. This story was an adventure filled with twists and turns we never saw coming. Check out the preprint and a summary below! biorxiv.org/content/10.110…

Excited to share our new paper: mTOR activation induces endolysosomal remodeling and nonclassical secretion of IL-32 via exosomes in inflammatory reactive astrocytes Project led by ⁦Kun Leng⁩ & ⁦Brendan Rooney⁩. jneuroinflammation.biomedcentral.com/articles/10.11…

Had a great time at GRC Neurobiology of Brain Disorders and was honored to receive the poster award from these fantastic individuals. I'm also honored to have been elected to co-chair the associated GRS in two years. Looking forward to that!!

Tenure-track faculty search of the UCSF Biochemistry Department is open for applications! We are looking for creative, innovative scientists asking fundamental questions in any area of biology. Join our vibrant, collaborative, and supportive community! aprecruit.ucsf.edu/JPF05209

The new and improved version of GEARBOCS, an AAV tool for in vivo genome editing in astrocytes, is here, and the plasmids will be available in @addgene soon! Check out the preprint by amazing Dr.Dhanesh S B and co! biorxiv.org/content/10.110…