Indumathi Mariappan
@indumathi76
Researcher
ID: 1523365282789482497
08-05-2022 18:13:34
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.Collaborative work by the LV Prasad Eye Institute, India and NEI showed that gene ABCA4 is involved in Photoreceptor outer segment (POS) and lipid handling in retinal epithelial (RPE) cells. Dr Jitendra Singh Rajesh Gokhale doi.org/10.1016/j.stem…
.Scientists at LVPEI reported generation of miniature retinal tissues using engineered stem cells which hold promise for developing new therapies, testing novel drugs and to understand disease physiology. Dr Jitendra Singh Rajesh Gokhale jove.com/t/64509/genera…
Investigators from LVPEI report generation of patient specific induced pluripotent stem cell line (LVPEIi002-A) from a patient diagnosed with retinoblastoma carrying heterozygous mutation in RB1 gene #stemcell Dr Jitendra Singh Rajesh Gokhale
Patient specific iPSC lines carrying a homozygous splice site mutation within the LCA12 candidate gene, RD3 protein opens up potential avenues for development of in vitro disease models for Leber congenital amaurosis. Dr Jitendra Singh Rajesh Gokhale LVPEI
Retinoblastoma, a malignant tumour of the developing eye occurs in children. To study its pathophysiology, three RB1 null iPSC lines were generated through targeted editing of RB1 gene in a healthy control iPSC line, RUCDRi002-A. Dr Jitendra Singh Rajesh Gokhale LVPEI
Engineered FnCas9 in patient-specific stem cells broadens the potential for precision editing, promising innovative treatments for genetic conditions. Read more at: doi.org/10.1038/s41467… Dr Jitendra Singh Rajesh Gokhale
