DESTINY-Breast 03 TDXd vs T-DM1
OS median not reached in either arm, but statistically significantly better with TDXd (HR 0.64)
mPFS 28.8 mo vs 6.8 mo
ORR 78.5% vs 35%
CR 21% vs 9.5%

ILD 15.2% (no grade 4/5 events)

Great presentation by Sara Hurvitz

OncoAlert #bcsm #SABCS22

Sorry the pun 🥸🤡, but for me this was RIGHTly the most interesting data from the 1st day of #SABCS22 .

Visceral crisis is a dramatic situation where chemo has always been the choice, but which ribo plus letrozole has shown to be more effective with less AEs
OncoAlert #bcsm

Many important findings from the updated results of #TAILORx . After 11 years of follow up, still no benefit from chemo in patients with RS 11-25. Some benefit in younger patients with RS 21-25 (OFS?). Late recurrences >5 years exceeded early recurrences. #SABCS22 #bcsm

12-year follow up confirms that patients w/ recurrence score of <25 can omit chemotherapy, with some chemo benefit for premenopausal women (<50yrs) with RS 21-25. #SABCS22

Happy to share our now published #DB03 update!

@oncoalert #SABCS22

Trastuzumab deruxtecan versus TDM1 in patients with HER2-positive metastatic breast cancer: updated results from DESTINY-Breast03, a randomised, open-label, phase 3 trial - ScienceDirect sciencedirect.com/science/articl…

nejm.org/doi/full/10.10…

MOROCCO SEND SPAIN HOME 🇲🇦

The word for sick in Persian/ Farsi is “Bimar.”, which literally translates to “without a snake”. This is due to the fact Persians kept a snake in their yard/garden and believed rats carried diseases so if someone was sick they didnt own a snake to protect their home. #MedTwitter

Awful news that the great Pelé has been moved to end-of-life palliative care after he stopped responding to chemotherapy. The only footballer in history to win 3 World Cups, and an icon of the game at the level of Muhammad Ali in boxing. So sad. 🥲

I always wonder how someone with a personality of a lobotomized rock becomes a physician #MedTwitter

3 years ago on November 30: A man in Wuhan, China starts feeling ill and later becomes the first confirmed case of COVID-19. More than 6.6 million people have since died #MedTwitter

Oncall 📞 days #oncology #MedTwitter #theemperorofallmaladies

❤️

Racist much? Here is the former failed USA national coach spewing hatred

The commentary, this is the best video of 2022.

Japanese fans at the opening World Cup match cleaned up the stands after Qatar-Ecuador. 🇯🇵

Most respectful fans in the world. 👏

🎥 IG/qatarliving
x.com/actufoot_/stat…

A wonderful tour of England, Ireland and Scotland done ✔️ 🏴󠁧󠁢󠁥󠁮󠁧󠁿 🇮🇪 🏴󠁧󠁢󠁳󠁣󠁴󠁿 ❤️ #travels

He would make a great outfielder 😂

It takes a special kind of person to wake up early and still be late 🙋🏻‍♂️ 😂 #medtwitter

One of the first new patients I encountered after completion of my fellowship was a 20 year old college student with newly diagnosed Hodgkin’s lymphoma requiring intensive chemotherapy. Today, 9 years later, I discharged her from my clinic 😍 #medtwitter #remissionisbeautiful