This week's most shared article: Mucosal Biofilms Are an Endoscopic Feature of #IrritableBowelSyndrome and #UlcerativeColitis: ow.ly/AAhl50PU8o9 By authors from @meduni_wien

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🔬 Exciting news! 🎉 Our preprint is out, enabling mechanistic studies of #archaea in the human #microbiome. 🧫 We introduce a cultivation pipeline yielding previously uncultivated Methanobrevibacter strains and shedding light on their role #archaeome

Saori Kashiwagi showed some really amazing data that #mucus degrading #Ruminococcus gnavus cross feds #AIEC - this could be particularly relevant in #IBd. #DDW2024

Gastrointestinal biofilms are relevant in several GI conditions. #MedTwitter #GITwitter #microbiome sciencedirect.com/science/articl…

Together with @OrglerElisabeth and Christine Moissl-E we show that presence of Methanobrevibacter influence mucosal #biofilm and might be linked to gut hypoxia Archaea influence composition of endoscopically visible ileocolonic biofilms doi.org/10.1080%2F1949…

Our review about endoscopically visible mucosal #biofilms is out in Gastroenterology. We discuss pathophysiology, potential treatments and highlight knowledge gaps and open research questions gastrojournal.org/article/S0016-… MedUni Wien Universität Wien

🌟 Review on gastrointestinal biofilms covers #endoscopic detection, disease relevance, and therapeutic strategies. Read it the article here: ow.ly/N8t250TPPx9

Check out the CME questions on GI biofilms accompanying our review in Gastroenterology gastrojournal.org/cme/home

If you ask many highly educated IBD patients, they will hypothesize that biofilms are a relevant factor in some IBDs. Here is an important study and much more attention is warranted on this topic.

Looking forward to present my talk about "Epimerization of Host-Derived Bile Acids By R.gnavus as a Hallmark of Microbiota Dysbiosis" at #KSHumanMicro25 #KSHostMicrobe25 Connecting bacteria to specific metabolites, will enhance out mechanistic understanding of #IBD / #IBS

An altered gut mucus and microbial biofilms might be one root behind the rise #IBD John Damianos, M.D. & colleagues review dietary interventions that work (and don't work) for strengthening gut barrier mucus: 🔴 Dietary factors damaging the mucus layer: 🔸 Emulsifiers (e.g.,

🌎 Today, on World IBD Day, I am raising awareness for an often overlooked and underrecognized condition in IBD: bile acid malabsorption (BAM). Timely diagnosis and the use of current treatments, such as dietary interventions and medications, are crucial in improving quality of

doi.org/10.1111/nmo.70… We show lower transit time alone decr. microbiome diversity + BA metabolism and incr. fecal BA. Many 'omics studies and breath testing (SIBO) don't take this into account, hindering true progress on IBS/IBD pathomechanism. Neurogastro & Motil ESNM.eu ANMS

Delighted to have our latest work on therapeutic targeting of the nuclear Bile Acid receptor, FXR, published in AJP-Gastrointestinal and Liver Physiology . Thanks so much to our collaborators Triona Ní Chonghaile Intercept Pharma Luciano Adorini and funders Research Ireland for their help. RCSI School of Pharmacy and Biomolecular Sciences

Does the future of #SIBO diagnosis and treatment lie in endoscopy?! onlinelibrary.wiley.com/doi/10.1111/nm…

doi.org/10.1111/nmo.70… In this comment we suggest that SIBO and IBS share ileal bacterial biofilm formation as pathomechanism, which correlates with increased biomass and disrupted bile acid metabolism. currently studying if biofilm removal via endoscopic lavage improves sys