Looking for a motivated person to join my #Algorithms and #MachineLearning team to further improve our industry leading Oxford Nanopore modified base detection capabilities!

Really happy to see RRMS out! I'm sure will enable a bunch of new applications in epigenetics 🧬 Check out all the advantages of this adaptive sampling method for cost-effective methylation calling using #nanopore technology ! Spoiler: lots!

Excited to share our paper, out today in nature, where we characterize transcriptome variation in human tissues by long-read sequencing. Huge thanks to Dafni Beryl Cummings Garrett Garborcauskas Daniel MacArthur and other collaborators. 🧵 nature.com/articles/s4158…

Come and join us – awesome community, great resources, and a cool city! Besides, in this crazy world is there a better place to be than Canada? 🇨🇦

Blog post - 20 years of open science or how we haven't radically changed the way we do science online. Thoughts on how we don't seem to be using the internet to its fullest potential in scientific collaborations evocellnet.com/2022/11/20-yea…

Minimap2 #Rust bindings update to v0.1.11. HTS lib support (SAM/BAM writing) and mm2-fast support via feature flag. Huge thanks to Eoghan Harrington for the HTS lib support! Check out the full announcement: sci.kiwi/@josephguhlin/… #bioinformatics #nanopore #genomics

Incoming…

This should save me some time

New addition to the Oxford Nanopore Open Datasets: Genome in a Bottle Ashkenazi Trio, accessible via @AWSCloud. Sequencing was performed using #PromethION Flow Cells, (~200Gb yield each), Kit V14 chemistry & analysis driven by Nextflow. Read here: bit.ly/3E96oyG

47,000 nanopore genomes processed a year (84k so far).

Come talk 🦠💻🧬 with me at #ASMicrobe! I'll be: 1. At my poster: adaptive sampling, MAGs, and host methylome from human microbiomes (Sat, HMB06) 2. Intro-ing metagenomics pipelines for Nanopore data (Sat/Sun, Data for Breakfast, 10:05-10:20 @ booth 2207) 3. At the Nanopore booth

#ASMicrobe folks: come see Christine He at her poster to learn how Oxford Nanopore sequencing of human microbiome samples can simultaneously: - Deplete host DNA to get more microbial reads - Generate genome-resolved assemblies - Provide host DNA methylation from the proximal tissue

Bacterial epigenomes are very cool and extremely diverse! And you get them for free when you do Oxford Nanopore sequencing 🧫🧬

Another LOADED update from the Oxford Nanopore EPI2ME team with wf-metagenomics and wf-somatic-variation getting new functionality & our desktop app getting easier for Windows users & displaying workflow progress. All this and more here: labs.epi2me.io/epi2me-23.07-0… We’re also hiring…

Here The Banfield Lab used #nanopore sequencing to study 'the nature and existence of enigmatic genetic elements' (Borgs) in soil. They assembled 7 new curated Borg genomes, revealing extensive DNA methylation that differentiates them from their host archaea, Methanoperedens. 🧵1/2

✂️Splice splice baby!✂️ New paper just out in Cell Stem Cell integrating Oxford Nanopore long read single-cell isoform mapping into our broader genotype-phenotype vision for clonal mosaicism ! authors.elsevier.com/a/1hat96tu0Cm5…

Two more openings in our applications development team. Come help us build new computational methods and software to fully leverage the tremendous recent improvements in Oxford Nanopore sequencing! ejnh.fa.em2.oraclecloud.com/hcmUI/Candidat…

Come and work with us! It's an amazing team and an incredible opportunity to develop computation tools that will have real world impact in a wide range of areas as well as being part of pushing the boundaries of what is possible with DNA and RNA sequencing.

What if you could characterise brain tumours in hours, rather than weeks? And in doing so allow neurosurgeons to adjust their surgical strategies on the spot. Here, researchers showed that they were able to do just that by leveraging nanopore technology: bit.ly/46BH8x4

Now, Oxford Nanopore only approaches are producing the best t2t automated assemblies ever produced with 30 contigs and 5 scaffolds! 🤯🤯🤯🤯 #nanoporeconf