It's new-preprint-from-the-lab day! (In my opinion the most fun + authentic day to celebrate a new publication.) Check it out: "Large-scale control over collective cell migration using light-controlled epidermal growth factor receptors" biorxiv.org/content/10.110…

Most important message for scientists to share with the general public! Thanks Cajal, The Nobel Prize.

Our eLife - the journal paper on artefactual Ca2+ waves following calcium indicator expression is highlighted in neuroscience magazine The Transmitter. Really nice talking with Angie Voyles Askham and seeing the perspectives from trent, @DanielDombeck & LoogerLab thetransmitter.org/methods/widely…

New paper out in Nature Neuroscience! Collaborating with several labs, we developed genetically encoded biosensors to track opioid pharmacology in the brain & provide powerful new tools for dissecting complex circuit-specific dynamics 🔧🧠 nature.com/articles/s4159…

5/ We must remember that all biological structure and physiology arise from dynamic processes happening at all length scales from single molecules to whole organisms…

8/ But environment matters too. Cells in the eye and brain have the same DNA but look and behave wildly different. The phenotypes we see are the result of gene expression, which is regulated by local environmental cues. If we don’t recapitulate the proper environment, how can we

I always had a hunch that phosphatidic acid regulates ion channel function. This paper from Tibor Rohacs and colleagues shows this nicely. nature.com/articles/s4146… #IonChannels

Ghosting your draft 👻

"Postdoc positions can be exploitative." My latest story—about a study showing that international postdocs in the U.S. are paid less and received less careeer support and guidance than U.S. citizens. #AcademicChatter #postdocs Science Careers science.org/content/articl…

WHaloCaMP is a chemigenetic calcium indicator based on HaloTag that can be combined with different rhodamine dyes for multiplexed or FLIM imaging in vivo, as demonstrated in neuronal cultures, brain slices, Drosophila, zebrafish larvae and mouse brain. nature.com/articles/s4159…

Super-excited to reveal our latest fluorescent voltage indicator, ASAP5, now online Neuron! ASAP5 features higher responsivity and kinetics, allowing detection of single synaptic transmission events. The link gives free access until 2024.11.09: authors.elsevier.com/a/1joYd3BtfH9B…

Read about the latest circuit tools for studying neuromodulator & neuropeptide signaling in vivo! We describe the use of neurochemical sensors, actuators, and probes in our lab’s first Review Science Magazine tinyurl.com/4mcfb24w Congrats Jessie Muir & Maribel Anguiano!

Can we map gut inflammation with ultrasound? Yes, using probiotic biosensors! 🔊 Imagine drinking a "diagnostic yogurt" and getting an ultrasound instead of endoscopy or colonoscopy 😁. Congrats to Marjorie Buss and collaborators on this advance. doi.org/10.1101/2024.0…

Blown away by the response to our preprint - I always forget one of the best parts of science is seeing others genuinely excited about your work Thought it might be a fun time to repost my 2022 essay on where spatial technologies may go in the future: chianglab.bio/2024/09/26/spa…

Science is built on trust. What happens when someone destroys it? My first feature for The Transmitter investigates the emotional and existential fallout for one lab in the aftermath of a misconduct case. thetransmitter.org/science-and-so…

Doing good science is 90% finding a science buddy to constantly talk to about the project.

Free scientific illustrations for biologists! 😍 NIH has released a library of 500+ free scientific illustrations to create figures, presentations, and illustrations! all freely available in the public domain. Retweet and spread the message! bioart.niaid.nih.gov

Looking for a fluorescent biosensor and don’t know where to start? Want a comprehensive overview of the field? Check out our new review in Chemical Reviews online now as an ASAP article! From co-first authors Dr. Anneliese 💖💜💙 @AyseZSahan Yanghao Zhong doi.org/10.1021/acs.ch…

Resumes shouldn't just showcase our success. They should feature our struggles too. No one's life is a highlight reel. Character isn't visible in our triumphs alone—it's revealed by the hardships we endure and the challenges we conquer. Here’s my lowlight reel. What's on yours?

Introducing my lab's first independent publication, featuring photopharmacology of GABA(A) receptors. Congratulations to my PhD student (Simon Lopez) and founding lab member (Jay-Rong Lee), what a great job! 👍👍👍 bpspubs.onlinelibrary.wiley.com/doi/abs/10.111…