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Happy to share our recent work on mitochondrial translation termination by franzinadler et al.: biorxiv.org/content/10.110… We solved a long-standing mystery and explain the function and specificity of canonical and non-canonical mitochondrial release factors (mtRF1a vs mtRF1).

Latest Biomed News in #Cancer #Bioenergetics - biomed.news/bims-mibica/20…. Lab pick from eLife - the journal demonstrating that mtDNA deletions are genetically regulated as a defense against short-term ROS damage (in yeast). Very cool! elifesciences.org/articles/76095

This is a very cool study from @MFryeLab in nature showing that modifications of mitochondrial tRNAs regulate cancer metabolism and metastasis by promoting ETC expression and oxidative glucose utilization. OA: rdcu.be/cRfsu nature.com/articles/s4158…

A high-resolution map of human RNA translation dlvr.it/SWCdMn

Fantastic paradigm shift in understanding mtDNA gene expesision! Mito@GU, Minczuk Lab, @NCL_mtDNA.So happy that the first author Ben Tan Benedict Tan wiil join my group in 10 days! cell.com/molecular-cell…

For students wondering if PIs still get nervous, I gave a short talk today...

On our way!!! #CSMito2022 Cell Symposia Cell Press

Premio de Investigación “Margarita Salas” 2022 de la Comunidad de Madrid a José Antonio Enríquez cnic.es/es/node/183140

We are very happy and proud that Luca was recognised with the very first Margaret Lewis award for the recognition of excellence in the mitochondria biology field Gordon Research Conferences

A Two Year Post-doctoral Position is available in the Soriano Lab, Department of Biology – University of Padova, Università di Padova. This is a unique opportunity 👇Stellar Lab and Stellar PI. APPLY!!!!!!

PostDoc position available to TMEM65 protein and related disorders in Soriano Lab ! 🇮🇹🍕With great collaborators Milena Bellin Telethon-Cariplo Grant. Fondazione Cariplo @Telethonitalia Department of Biology – University of Padova

labsoriano.com/open-positions

Excited to share one more 2023 research story from our lab, out today Cancer Discovery identifying #Mitochondria and #Mitophagy as a key regulator of Venetoclax and MCL1i resistance in AML. The work was led by Christina Glytsou and xufeng chen ...NYU Grossman School of Medicine (1) aacrjournals.org/cancerdiscover…

Mito dynamics seems crucial for cancer resistance to therapy. Check our recent papers from masafumi noguchi on how our Opa1 inhibitor MYLS22 reverts gefitinib resistance in NSCLC rdcu.be/daF7C and from MargheritaZamberlan on how MYLS22 treats TNBC models rdcu.be/daF8z! 2/3

Congratulations Ildiko Szabò (SzaboLab) for being elected to join #EMBO. Szabò’s research focuses on discovery, characterisation & pharmacological targeting of #mitochondrial ion channels in context of #cancer & #autoimmune diseases.