Great to see this out! Variant function, population genetics and animal models investigating the role of LXR alpha in liver health! Thanks to co-first author Milan Muso, my PhD supervisor stephen o'rahilly (its pronounced O-RA-hill-EEE) and many collaborators! Inst Metabolic Science-Metabolic Research Labs Nature Metabolism nature.com/articles/s4225…

Not for the first time, all Nobel Prizes in scientific disciplines this year have been awarded to men

Our poster today on behalf of all on the GeNotes Endocrinology Working Group: GeNotes are tools by endocrinologists, for endocrinologists, on the how, why, and when of ordering genetic tests BSPED Genomics Education NHS England Sasha Howard 💙🇺🇦🌻

Did you know? #Menopause increases the risk of #HighBloodPressure. Check your blood pressure numbers and take steps to stay healthy 🏃‍♀️. Visit the National Women’s Blood Pressure Awareness Week page to learn more! #HeartHealth #NWBPAW womenshealth.gov/nwbpaw womenshealth.gov

Read our statement about an article in The Guardian about potential misuse of UK Biobank data: ow.ly/Z35s50TNSXW

We at Wellcome have joined many UK science organisations in signing a letter to the chancellor ahead of the budget at the end of the month. It is crucial that the UK has stable, predictable investment in R&D, not wasteful stop-start funding. ft.com/content/fc00e5… via @ft

Word of the day is ‘recrudescence’ (17th century): the return of something terrible after a time of reprieve.

Lovely talk from Jen Suntharalingham and our group on insights into gene expression in monosomy X during human fetal development 👏👏ESPE @GGM_ICH

So what is the actual process for nominating someone for a Nobel prize, can we all just write in or what?

Muscle-derived myostatin is a major endocrine driver of follicle-stimulating hormone synthesis | Science science.org/doi/10.1126/sc…. Major advance in endocrinology. So fascinating that new important hormonal actions of TGFBeta family members are still being discovered./

Agree that it’s great to see this. Delivering 2.3 will be key. I don’t doubt the funders desire to see this happen. I worry about the reality of commitment from NHS. Colleges and particularly HEE, which seems to be intent on stifling excellence and academic aspiration

I am excited to share our latest paper nature where we construct a hi-res spatial map of the human hypothalamus, the brain region central in appetite control. It is a collaboration between Inst Metabolic Science-Metabolic Research Labs Cambridge University & Max Planck Institute for Metabolism Research nature.com/articles/s4158…

We present to the world, HYPOMAP! #obesityisnotachoice cam.ac.uk/research/news/…

An exam taken 2 years ago incorrectly assigned 61 people as having failed who actually had passed Worse still, >200 who were told they’d passed actually failed. I’m going to keep asking this very simple question: what are my membership fees being used for, if the RCP can’t

Our lack of universal GP care is the subject of this Lancet editorial. "Health spending is ultimately a political choice. It is time that Ireland moves from being an outlier in Europe to providing universal access to primary healthcare." Doctors for Universal Healthcare thelancet.com/journals/lanep…

Opinion: ‘Universal GP care for Ireland is long overdue’⁦Domhnall McGlacken-Byrne⁩ thejournal.ie/readme/univers…

Clinical research in the UK is under threat, partly because it takes so long to get a study or trial approved. Here are some of my suggested solutions in this BMJ Opinion piece NIHR Wellcome UK Research and Innovation bmj.com/content/388/bm…

Thank goodness people are waking up to the fact that there is a crisis for clinical research in the UK Financial Times High on the list are the bureaucratic processes that have become such an obstacle to getting things done

Here is a letter I wrote in the Lancet this month, on how the imprint of Ireland's history can be seen in our health services, particularly primary care. Primary care in Ireland: history explains the system we see today Doctors for Universal Healthcare The Lancet Reg Health-Europe thelancet.com/journals/lanep…

A brief tiny memory about Manchán Magan, who passed away yesterday. I guested on a series he did 20 years ago, and he noted that I had dropped the “fada” (the accent/diacritic) over the O in my name, which I had replaced with a capital O, just for ease of understanding in the