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New blog article challenging medical researchers who are drawn to clustering patients to create so-called "phenotypes" to think again: fharrell.com/post/cluster Maarten van Smeden “Darren Dahley” #Statistics #PrecisionMedicine @vandy_biostat

We still routinely see age-old errors crop up in trial reports. Despite many people highlighting these problems time and again, they still keep coming 1/7 #MethodologyMonday #104

Bayesian Analytical Methods in Cardiovascular Clinical Trials: Why, When, and How By John Mandrola, MD Frank Harrell et al. Via CJC Journals onlinecjc.ca/article/S0828-…

Logistic regression still the GOAT😤: When you fix the problems in papers claiming "ML predicts XYZ amazingly well", you end up with ML ~= LR cell.com/patterns/fullt…

The best advertisement for my book … #Statistics #rstats

We have seen a number of trials with non-significant findings at #CCRdownunder. There is often debate then about what next? This paper by Pocock & Stone is a useful discussion piece to inform this type of discussion nejm.org/doi/full/10.10…

We would like to CONGRATULATE our 1st place 2024 Best of Hypertension winners in the category of Clinical Science: ahajrnls.org/3HprrOH Stefano Omboni MD FESC ISHF @martingschultz Dean Picone

👩 Women suffered from a bias regarding the prescription of high-intensity lipid-lowering therapy after AMI, which did not attenuate between 2005 and 2015, with potential consequences on both survival and risk of cardiovascular events 💊 Check out #EJPC paper:

So pleasing to see JACC Journals 🔦 #Hypertension #BloodPressure 🙏 & the recent ⭐️ ESC #GLs Wonderful summary Yuan Lu @SpatzErica Harlan Krumholz 👏 The Touyz Lab John William McEvoy Cian McCarthy Rosa Maria Bruno & all coauthors further👇 confirmation for your efforts!

Winter athletes face cardiovascular challenges, primarily related to cold temperatures and altitude-associated hypobaric hypoxia. This review highlights key considerations for the cardiovascular care of winter athletes, & more. ➡️ 🔗 bit.ly/4cTSYWy

A new Roadmap paper on 'Developing technologies to assess vascular ageing': iopscience.iop.org/article/10.108… Covering: - measurement technologies - the development pipeline - clinical applications - future research directions. Including contributions from 46 experts. VascAgeNet

Now in Hypertension, Rosa Maria Bruno Kazem Rahimi The Touyz Lab and John William McEvoy discuss what is new and different in the 2024 ESC Hypertension guideline compared to the 2017 ACC/AHA and 2023 ESH Hypertension guidelines ahajournals.org/doi/10.1161/HY… 1/

Global and European landscape of major hypertension guidelines - The Lancet thelancet.com/journals/lance… European Society of Cardiology University of Galway CMNHS NIPC Johns Hopkins Ciccarone Center Cian McCarthy Rosa Maria Bruno The Touyz Lab Ollscoil na Gaillimhe | University of Galway University of Galway Research & Innovation

Gestational hypertension and preeclampsia are both linked to greater cognitive decline and brain MRI white matter hyperintensities, starting as early as in midlife #BrainHealth Xiaqing Jiang Kristine Yaffe UCSF Center for Population Brain Health (K. Yaffe) Kaiser Permanente Research NorCal ahajrnls.org/4h5e1rF

What is the evidence behind new categories of elevated blood pressure in the ESC Hypertension Guidelines? Emmanuelle Vidal-Petiot Ph.Gabriel Steg Hôpital Bichat - Claude-Bernard AP-HP ahajournals.org/doi/full/10.11…

The VITAL study has now been running for 1 year! What have the team been up to? Find out in our latest newsletter here: vital-horizoneurope.eu/wp-content/upl…

VIrtual Twins as tools for personalised clinicAL care (VITAL). The team at the 1st VITAL Consortium meeting in Barcelona. VITAL

In honor of World Preeclampsia Day (ahajrnls.org/3GfN2Mm), we've dedicated a whole issue to the Advance of Pregnancy Hypertension! ahajrnls.org/3Y0ZSnR. Make sure to check it out today!

A major update to the CONSORT reporting guidance for clinical trials was published last week. 📌 CONSORT 2025 replaces all previous versions and should be used from now on. So what’s new and what’s different? 1/7 #MethodologyMonday #116 (COI - I am a co-author)

RESEARCH ARTICLE: Early Pregnancy Blood Pressure Trajectories and Hypertension Years After Pregnancy ahajrnls.org/3Gf2RmG