NCI R01 payline raised to 12th percentile. Highest since 2010. Very good but probably not enough for the progress we need to achieve in cancer. cancerletter.com/the-cancer-let…

About 30 years ago, Katherine Cullen et. al. demonstrated a nuclear ligation assay to study long-range chromatin interactions. Many 3D Genome methods still employ the same concept. science.org/doi/10.1126/sc…

Pleased to share our manuscript on the Critical role of antioxidant programs in enzalutamide-resistant prostate cancer. rdcu.be/dfgGw Eliot Blatt UTSW Simmons Cancer Center PCF Science UTSWCancerBio this was Eliot’s thesis project and was based on his unbiased metabolomic studies

Thanks to my team members (current and former), collaborators, colleagues, mentors, family and everyone who helped me in this journey from Assistant Professor to Associate Professor!

The incidence of endometrial cancer continues to rise each year. Ram Mani, Diego Castrillon & team UT Southwestern Medical Center establish a new mechanism of tumor-suppressor inactivation in which epigenetic reprogramming silences PAX2 and initiates endometrial carcinogenesis:

Behind the Scenes with principal contributors from the Mani and Castrillon labs at UT Southwestern. Left to right, Ram Mani, Diego H. Castrillon, Susmita Ramanand, and Subhransu Sahoo.

ICYMI: The incidence of endometrial cancer continues to rise each year. Ram Mani Diego Castrillon & team UT Southwestern Medical Center establish a new mechanism of tumor-suppressor inactivation in which epigenetic reprogramming silences PAX2 and initiates endometrial carcinogenesis:

Congratulations to KidneyCancerProgram UTSW Hematology & Oncology investigators on their Cancer Discovery paper bit.ly/MalCanDiscovHCM establishing a role for #HIF2 in PTHrP regulation and hypercalcemia in #renalcancer & KaelinLab in press Nature Medicine.