MTCH2 controls energy demand and expenditure to fuel anabolism during adipogenesis embopress.org/doi/full/10.10…

SLC25A38 is required for mitochondrial pyridoxal 5’-phosphate (PLP) accumulation nature.com/articles/s4146…

An avoidance segment resolves a lethal nuclear–mitochondrial targeting conflict during ribosome assembly nature.com/articles/s4155…

Serine phosphorylation facilitates protein degradation by the human mitochondrial ClpXP protease pnas.org/doi/10.1073/pn…

In some positive news - truly honored to be named a 2025 ASBMB Fellow. Humbled to be a part of this amazing cohort of researchers. -ok

Structure of mitochondrial pyruvate carrier and its inhibition mechanism nature.com/articles/s4158…

Engineering mtDNA deletions by reconstituting end joining in human mitochondria cell.com/cell/fulltext/…

1/ We are excited to share our latest work, showing that heterooligomerisation drives structural plasticity of Prx1-type peroxiredoxins. biorxiv.org/content/10.110… This was another fantastic collaboration with; the Deponte Lab and Messens Lab.

Structure of human PINK1 at a mitochondrial TOM-VDAC array science.org/doi/10.1126/sc…

Structural mechanism of mitochondrial membrane remodelling by human OPA1 nature.com/articles/s4158…

As promised, a 🧵 on our recent article now out in NatureStructMolBiol! Co-led with Abby Bartlett Pagliarini Lab Judith Simcox PhD, we find ACAD10/11 are NOT like other acyl-CoA dehydrogenases and instead catabolize atypical lipids called 4-hydroxy acids 🤯#lipidtime doi.org/10.1038/s41594…

Online Now: Interaction with AK2A links AIFM1 to cellular energy metabolism dlvr.it/TLZdCW

Kudos to Anna Pellattiero C Quirin Federico Magrin, great collaborators S Moro A Mattarei Mattia Sturlese Evris Gavathiotis for our latest Science Advances paper science.org/doi/10.1126/sc…. Many years in the making but finally we have OPA1 inhibitors reverting cancer chemoresistance! 1/

Mitochondrial origins of the pressure to sleep nature.com/articles/s4158…

Type 2 diabetes is often considered a protein misfolding disease. But where are these toxic proteins found? 🤔 🚨In new work out today in Nature Metabolism, we show that mitochondrial protein misfolding (yes mitos🤯) leads to beta cell damage in T2D. 🚨 nature.com/articles/s4225… 1/n

#Mitochondria researchers listen up: Stoldt et al. established protocols for #superresolution microscopy of mitochondria, combining #smFISH with #STED and #MINFLUX. STED-smFISH reveals the spatial relationship of specific mRNAs and proteins, MINFLUX-smFISH shows mRNA folding

Proximity-specific ribosome profiling reveals the logic of localized mitochondrial translation sciencedirect.com/science/articl…

Dynamic TOM–TIM23 supercomplex directs mitochondrial protein translocation and sorting nature.com/articles/s4159…