1/2 This month we celebrate the 50th anniversary 🎂 of the publication of this landmark paper by Pasko Rakic where he described the migration of pyramidal neurons along radial glia in the fetal monkey cortex. Journal of Comparative Neurology Wiley Neuro onlinelibrary.wiley.com/doi/10.1002/cn…

Direct comparison of the acute effects of lysergic acid diethylamide and psilocybin in a double-blind placebo-controlled study in healthy subjects go.nature.com/37Du8OI #MentalHealthMonth

#JNeurosci Methodological Advances | Rapid and Gentle Immunopurification of Brain Synaptic Vesicles jneurosci.org/content/42/17/…

#FragPipe 18 release: new visualization module (view/export MS/MS spectra, special options for glycopetides, protein coverage, sorting, etc.)! New: "headless" option to run command line - great for automation/HPC/cloud. New workflows. Upgrades in all tools fragpipe.nesvilab.org

1/4: Today marks 3 years since I started working with @rhodamine110 HHMI | Janelia! A lot has happened since then, including the ongoing pandemic! Coincidentally, on this 3rd anniversary, my first project and my first preprint is online bioRxiv. biorxiv.org/content/10.110…

Spectronaut no longer free, Gee! Thermo tripled PD price, Nice… They won’t hear your mercy plea, Flee! Academic tools suffice, My advice.

I use polarised filters to explain (some) quantum mechanics to my kids. How is it possible that adding a 3rd filter in between (the one at 45º) some light get to go through the otherwise black rectangle in the middle?

If like me you've run hundreds of minipreps but never bothered to read up on why they extract plasmid but not chromosomal DNA, a recent tweet by @joel_rosenbaum finally motivated me to look it up. From Biennium and Doly 1979:

Please share/retweet! We are looking for a postdoc, preferably w/ clinical training and eligibility for Maryland licensure to help run clinical trials of psychedelic-assisted therapies.

Alfonso Martinez Arias Richard Sever eLife - the journal that's the idea - we are intentionally redefining what eLife means - it means high-quality, constructive REVIEWS - not high-quality papers

Psychedelics are becoming decriminalizing in the US by state legislation at a dizzying and accelerating rate. See our analysis of legislation out today in JAMA Psych: jamanetwork.com/journals/jamap…

Because doctors cannot predict whether a given patient is among the 15% helped by the drugs, the only way to find out is to give them a try econ.st/3W17JOb

Excited to share our recent work, now out at eLife - the journal! Ever wonder how synaptic vesicle proteins are sorted to synapses?? We show that these proteins are selectively routed to axons and then delivered to the presynaptic plasma membrane. 👇🏻👇🏻👇🏻 doi.org/10.7554/eLife.…

The Oregon Psilocybin Services client info form asks about psychosis and indicates that this is exclusionary, but mysteriously omits history of mania/hypomania as an absolute or relative contraindication. Why? oregon.gov/oha/PH/PREVENT…

Very interesting case lead by Dr Josh Rosenblat from our team that the use of a 5HTA antagonist with psilocybin did not attenuate antidepressant effect in TRD raises interesting conceptual questions on mechanisms of psilocybin effects . pubmed.ncbi.nlm.nih.gov/36945824/

Our paper on extended difficulties after psychedelics now published in PLOS One. journals.plos.org/plosone/articl…

As psychedelic medicines enter the market, clinicians need informed consent processes tailored to non-research settings. Article describes 7 elements of informed consent to receive psychedelics. ja.ma/3UeMf2Z Mason Marks, MD, JD Rebecca Brendel MD, JD Carmel Shachar I. Glenn Cohen

Like, here's the mol bio mechanistic model of an airplane Bede Portz