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This Primer on MASLD Nature Reviews Disease Primers nature includes: ▶️ Mechanisms ▶️ Genetics ▶️ Epidemiology ▶️ Risk stratification algorithms ▶️ Non-invasive tests ▶️ Therapeutic options ▶️ Clinical trial landscape Rohit Loomba UCSD Gastroenterology Yong Loo Lin School of Medicine #LiverTwitter nature.com/articles/s4157…

Consensus panel recs: Diagnosis and Monitoring Pathways Using Non-Invasive Tests in Patients With A1AT-liver disease #livertwitter my_UEG AASLD EASLnews American Gastroenterological Association (AGA) pubmed.ncbi.nlm.nih.gov/40072894/

How are specific #SocialDeterminantsOfHealth assoc with prevalence & severity of #MASLD #MASH ? Our systematic review & meta-analysis is out in AJG - The American Journal of Gastroenterology journals.lww.com/ajg/abstract/9… 💠#diet quality: assoc with MASLD & MASH AF/cirrhosis 💠 ⬇️ #income assoc with clinical outcomes

Rohit Loomba presenting now at the #ALDALLY meeting in NYC about Pharmacotherapy for MetALD #LiverTwitter

Potential MetALD pharmacotherapies talk by Rohit Loomba at ALD_ALLY UC San Diego Health

Wonderful talk on #MetALD Rohit Loomba 🔴Rates of #MetALD likely severely underestimated ⚪️FGF21 and GLP1RA may play a role in reducing alcohol consumption mechanistically 🔵GLP1 and Glucagon co-agonism is promising

Congratulations to maral amangurbanova on matching into the Internal Medicine program at Mt. Sinai! 🙌👏Your contributions to MASLD Research Center have been invaluable. You’re destined for great things — you will be deeply missed!

Thanks for the invite Juan Pablo (JP) Arab, MD  ! Excellent meeting! AASLD EASLnews

Thomas Cech ⁦The Nobel Prize⁩ winner giving a keynote ⁦UC San Diego Health⁩ medicine research day - talking about his work on RNA and its impact on health and evolution ⁦MASLD Research Center⁩ ⁦UCSD Gastroenterology⁩ ⁦AASLD⁩ ⁦AASLD President⁩ ⁦Satya Nadella⁩

Honored 🙏 to have the opportunity to listen to Thomas Cech The Nobel Prize talking about "The Magic of #RNA: New Medicines, Immortality, and the Power to Control Evolution" at UC San Diego Health Annual Research Day. Truly inspiring insights! 💡🧬✨ MASLD Research Center #LiverTwitter #MedTwitter

UCSD MASLD Research Center representation at the UCSD DOM 3rd Annual Research Day! UC San Diego Health UCSD Gastroenterology Rohit Loomba Federica Tavaglione Veeral Ajmera Mónica Tincopa MD MSc

Excited to kickstart 16th Annual Research Symposium ⁦UCSD Gastroenterology⁩ on IBD and Immunology! Great to have outstanding speakers from across the nation ! Thanks ⁦Miguel Regueiro⁩ Scott snapper and Bill Sandborn for joining us ⁦UC San Diego Health⁩ ⁦American Gastroenterological Association (AGA)⁩

Delighted to co-chair the ⁦roypounder.apt⁩ editorial board meeting with Colin and colleagues from around the 🌎 - full house & great excitement- still remains the fastest decision GI journal no fees #ddw ⁦American Gastroenterological Association (AGA)⁩ ⁦ACG⁩ ⁦AASLD⁩

Happening now in SDCC 32 Digestive Disease Week #Obesity and Advanced #LiverDisease With Mazen Noureddin, MD, MHSc moderating Juan Pablo (JP) Arab, MD  discussing #ETOH and obesity Puneet Puri discussing #AOM & #MASH I will discuss the role of treatments that don’t also impact obesity in MASH 🤔

Great body of collaborative work from our international team that we organized MASLD Research Center Expert Consensus Delphi Panel in MetALD: Opportunities and Challenges in Clinical Practice pubmed.ncbi.nlm.nih.gov/40315973/ AASLD EASLnews Luis Antonio Díaz, MD Juan Pablo (JP) Arab, MD 

Rohit Loomba presented today at #EASLCongress exciting new data on the long-acting FGF21 analogue Efimosfermin alfa💊 showing improvements in fibrosis biomarkers⚡️ in subjects with MASH F2-F3, consistent with histologic fibrosis improvement EASLnews EASL Education MASLD Research Center UCSD Gastroenterology

Nice work led by Luis Antonio Díaz, MD and Veeral Ajmera MASLD Research Center UCSD Gastroenterology inherited risk predicts age-associated increases in fibrosis in patients with MASLD pubmed.ncbi.nlm.nih.gov/40334848/

Prescribing therapies for MASH but unsure of treatment response? The MASH Resolution Index, or FAST score may be helpful 🔥off the press HEPATOLOGY Journal Rohit Loomba AASLD journals.lww.com/hep/abstract/9…

Can FIB-4 then VCTE detect sig. fibrosis in MetALD? = Yes read Luis Antonio Díaz, MD paper MASLD Research Center Noninvasive pathway for stratifying fibrosis in suspected metabolic dysfunction and alcohol-associated liver diseas… pubmed.ncbi.nlm.nih.gov/40377491/ AASLD Elliot Tapper

At #EASL2025, AASLD President Dr. Grace Su chaired 2 sessions, EASL/AASLD Endpoints Conference on #MetALD & ALD, and General Session I, underscoring our commitment to #liverdisease. Thanks to all who grabbed the #TLM25 Preliminary Guide at the Hub—see you in D.C. in November!