Le Chang, PhD (@le_chang) 's Twitter Profile
Le Chang, PhD

@le_chang

Computational Genetics & Bioinformatics Postdoc @ICMtl | PhD @mcgillu MBI @queensu BSc @UAlberta | Developer of mirnet.ca (28k+ total users, 120 daily)

ID: 777135516

linkhttps://www.linkedin.com/in/le--chang/ calendar_today24-08-2012 01:28:09

107 Tweet

327 Followers

2,2K Following

Michael Snyder, PhD (@snydershot) 's Twitter Profile Photo

Fiber makes short chain fatty acids, we affects health. Our paper showing how this works (in part) at the level of gene expression is out: doi.org/10.1038/s42255…

DAN KOE (@thedankoe) 's Twitter Profile Photo

You don't magically become focused. You practice it. You notice you're distracted and snap out of it immediately, over and over again until it's second nature. Most people have not trained this muscle, and they are not anywhere close to as focused as they think they are.

Annika Vannan (@annikavannan) 's Twitter Profile Photo

It’s my pleasure to announce our recent work published in Nature Genetics: “Spatial transcriptomics identifies molecular niche dysregulation associated with distal lung remodeling in pulmonary fibrosis” 1/14 nature.com/articles/s4158…

Marios Georgakis (@mariosgeorgakis) 's Twitter Profile Photo

Dissecting the impact of genetic variation on disease risk by profiling genomics, transcriptomics, proteomics, and metabolomics in the very same 4,732 participants. This is a really rare resource by the INTERVAL study bringing all 4 major omics layers together!

Dissecting the impact of genetic variation on disease risk by profiling genomics, transcriptomics, proteomics, and metabolomics in the very same 4,732 participants.

This is a really rare resource by the INTERVAL study bringing all 4 major omics layers together!
University of Alberta (@ualberta) 's Twitter Profile Photo

Congratulations to U of A computing science professor Richard Sutton, a trailblazer in reinforcement learning, on receiving the 2024 A.M. Turing Award—often called the "Nobel Prize of computing"! His groundbreaking work continues to shape the future of AI. Read more:

Congratulations to U of A computing science professor Richard Sutton, a trailblazer in reinforcement learning, on receiving the 2024 A.M. Turing Award—often called the "Nobel Prize of computing"!

His groundbreaking work continues to shape the future of AI. Read more:
David Perell (@david_perell) 's Twitter Profile Photo

The world of writing has changed forever. AI is getting really good, really fast. ChatGPT is already a better writer than most humans and some professional writers. So, what’s the future of writing? 18 thoughts from Tyler Cowen: 1) Don't let AI smooth out your idiosyncrasies.

iMeta (@imetascience) 's Twitter Profile Photo

New Review on the "Gut–X Axis"! 🦠➡️🫀🧠🫁🦴 onlinelibrary.wiley.com/doi/full/10.10… The gut microbiota shape diseases beyond the intestine—impacting the brain, heart, lungs, kidneys, skin, and more. This review explores key mechanisms and clinical interventions. #GutHealth #Microbiome

iMeta (@imetascience) 's Twitter Profile Photo

MicroRNA‐microbiota interactions: Emerging strategies for modulating intestinal homeostasis and enhancing host health #iMetaOmics onlinelibrary.wiley.com/doi/full/10.10… #microbiome #microRNA #guthealth #microbiota

Xia Shen (沈侠) 🇺🇦 (@xiashen) 's Twitter Profile Photo

Our new method HDL-L, high-definition likelihood for local genetic correlation analysis, is now published in Nature Genetics: nature.com/articles/s4158…. The method enables unbiased and fast evaluation of genetic correlations at various genomic segments.

iMeta (@imetascience) 's Twitter Profile Photo

iMLGAM: Integrated Machine Learning and Genetic Algorithm‐driven Multiomics analysis for pan‐#cancer #immunotherapy response prediction onlinelibrary.wiley.com/doi/full/10.10… #MachineLearning #Bioinformatics @WileyBiomedical Wiley Clinical and Health

WCM Englander Institute for Precision Medicine (@wcmenglanderipm) 's Twitter Profile Photo

Researchers have discovered that a person’s 'bioenergetic age,' reflecting how efficiently cells produce energy, strongly predicts #Alzheimer’s risk and progression," according to Neuroscience News coverage of a recent Nature Communications paper by Jan Krumsiek! neurosciencenews.com/bioenergetic-a…

Joachim Schork (@joachimschork) 's Twitter Profile Photo

The ggblanket package is an extension for ggplot2 that simplifies the process of creating clean and consistent plots in R. It offers user-friendly functions that reduce the amount of code needed, making it easier to produce high-quality visualizations quickly. ✔️ Streamlines

The ggblanket package is an extension for ggplot2 that simplifies the process of creating clean and consistent plots in R. It offers user-friendly functions that reduce the amount of code needed, making it easier to produce high-quality visualizations quickly.

✔️ Streamlines
Eric Topol (@erictopol) 's Twitter Profile Photo

Of >105,000 participants with 30-year follow-up, only 9.3% achieved healthy aging (age 70, w/o any chronic diseases). Their diet was significantly associated with this outcome🧵 Nature Medicine

Of &gt;105,000 participants with 30-year follow-up, only 9.3% achieved healthy aging (age 70, w/o any chronic diseases). Their diet was significantly associated with this outcome🧵 <a href="/NatureMedicine/">Nature Medicine</a>
The Science of Parkinson's (@scienceofpd) 's Twitter Profile Photo

New review explores the relationship between kidney health & neurodegenerative conditions (like #Parkinsons & #Alzheimers) academic.oup.com/brain/advance-…

New review explores the relationship between kidney health &amp; neurodegenerative conditions (like #Parkinsons &amp; #Alzheimers)
academic.oup.com/brain/advance-…
Brain (@brain1878) 's Twitter Profile Photo

Zuo et al. review evidence for and against an association between kidney health and neurodegeneration, specifically dementia and the two most prevalent neurodegenerative disorders, Alzheimer’s disease and Parkinson’s disease. tinyurl.com/396j29ab

Zuo et al. review evidence for and against an association between kidney health and neurodegeneration, specifically dementia and the two most prevalent neurodegenerative disorders, Alzheimer’s disease and Parkinson’s disease. tinyurl.com/396j29ab
Andrew D. Huberman, Ph.D. (@hubermanlab) 's Twitter Profile Photo

The new Huberman Lab episode is out: How to Overcome Inner Resistance | Steven Pressfield (Steven Pressfield) 0:00 Steven Pressfield 4:55 Ideas & Resistance, Tree & Shadow Analogy 8:45 Military, Pushing Through Resistance, War of Art 10:14 Physical Training, Tools: Capturing Ideas,

Le Chang, PhD (@le_chang) 's Twitter Profile Photo

Interesting paper on the 'pooled vs. meta-analysis' debate for #multiancestry #GWAS — looks like the pooled approach (combining all data) comes out on top for statistical power cell.com/ajhg/fulltext/…