Congrats to Sindhana Pannir-Sivajothi for winning the PCCP student award at the #metamaterials2023 conference in Crete!

I'm delighted to release the first half of my new open-access online textbook in human population genetics: web.stanford.edu/group/pritchar…

BREAKING NEWS The 2023 #NobelPrize in Physiology or Medicine has been awarded to Katalin Karikó and Drew Weissman for their discoveries concerning nucleoside base modifications that enabled the development of effective mRNA vaccines against COVID-19.

Today we report in Nature Chemical Biology a collaboration led by Haoxin Li in Ben Cravatt's lab to illuminate functional and druggable cysteines in the human proteome by integrated base editing and activity-based protein profiling. nature.com/articles/s4158… PDF: drive.google.com/file/d/1hky1Ye…

BREAKING NEWS The Royal Swedish Academy of Sciences has decided to award the 2023 #NobelPrize in Chemistry to Moungi G. Bawendi, Louis E. Brus and Alexei I. Ekimov “for the discovery and synthesis of quantum dots.”

"Ponder for a long time whether you shall admit a given person to your friendship; but when you have decided to admit him, welcome him with all your heart and soul." Seneca on how to cultivate true friendship amid so much falsehood themarginalian.org/2017/05/19/sen…

Excited to share that I recently started a faculty position in the Rutgers University–New Brunswick MBB dept and the Rutgers CABM! My new lab will explore the fascinating biology of microbial defense pathways and engineer them for applications in human health & medicine. sites.rutgers.edu/tina-liu-lab/

Fun times today as Francesco joined Cianna at the pool table to practice the law of physics 😎. Cianna's journey of resilience continues to inspire all of us. Support her recovery at gofund.me/b04f2591. Let's keep the positive energy flowing! #phdlife #phdchat #compchem

We’ve a new review on DL methods for protein-protein interactions, focused on discovering novel interactions, structurally characterizing known interactions, and designing binders. Work by Julia Rogers, PhD and Gergő Nikolényi, who’ve done a great job distilling a huge field. More👇

Science is done... time for some fun! 1/2

It's always great to have our alumni with us! 2/2

On this day in 1938, Steinbeck completed 'The Grapes of Wrath,' which earned him a Pulitzer and became a cornerstone of his Nobel. Here is how he used the diary as a tool of discipline and a hedge against self-doubt: themarginalian.org/2015/03/02/joh…

If you have ever been betrayed by someone you have loved and trusted, this excellent reckoning by philosopher Martha Nussbaum is a salve themarginalian.org/2016/05/03/mar…

Genome editing has revolutionized the treatment of rare disease. What if we could put any change into RNA safely and reversibly? Today we (+ Omar Abudayyeh ) debut PRECISE, allowing for RNA edits, deletions, and insertions from 1 to >1,000nt biorxiv.org/content/10.110… 🧵 1/x

What a special day to remember! Today, Cianna, one of our #PhD #pirates, took her first steps outside since her health scare in November 2022. We roamed the Westfield UTC Shopping Center in La Jolla, enjoying the SoCal sun 🌞 (finally 😉), soaking in the sights and sounds,

In this review, Kartik Lakshmi Rallapalli & Komor Lab showcase DNA-editing enzymes that have been repurposed or redesigned and developed into programmable base editors doi.org/10.1146/annure…

Epigenome editing is transforming biological sciences and medicine. We're grateful for the opportunity to publish this review of the field in Nature Biotechnology. Check it out here: rdcu.be/dPjsJ

🚨 Update on our Summer 2024 #DataDriven #ManyBody Tour 🚨 Our first foray into de novo protein design! Cianna has combined simulations with deep learning tools to design protein binders for human EGFR. Five of her designs will be tested by Adaptyv Bio as part of their protein

Excited to share our latest study! Today in Nature Methods the Gerald Schwank and Krauthammer Lab report in Kim Fabiano Marquart et al. 'Effective genome editing with an enhanced ISDra2 TnpB system and deep learning-predicted ωRNAs' (1/6) nature.com/articles/s4159…

A new Science study presents “Evo”—a machine learning model capable of decoding and designing DNA, RNA, and protein sequences, from molecular to genome scale, with unparalleled accuracy. Evo’s ability to predict, generate, and engineer entire genomic sequences could change the