Excited to see this work from Richard G. James and dinodicarlo measuring antibody secretion with 10x Genomics assays!

Really cool stuff Hiroshi Sasaki!!!

Holy shit! I just learned that Carolyn Bertozzi - in addition to being a badass chemist and Nobel - was in a band with Tom Morello - guitarist from Rage Against the Machine 🤯

Pls RT: The Yewdell Lab is hiring 2 peeps! Unparalleled resources and collaboration, amazing benefits, beautiful campus, healthy work-life balance... AND DID I MENTION B CELLS!!! roche.wd3.myworkdayjobs.com/ROG-A2O-GENE/j…

Impactful words by Carolyn Bertozzi today on how diversity in her trainees enabled creativity, not playing by the rules, and ultimately the work that built the field of bioorthogonal chemistry. Diverse science leads to better science!

I don't use the phrase "tour de force" lightly... but it is warranted for this preprint by Kimberly Siletti et al. that just dropped from the Sten Linnarsson lab. biorxiv.org/content/10.110…

learning to code in R

BRCA2 chaperones RAD51 to single molecules of RPA-coated ssDNA biorxiv.org/content/10.110…

Hello from #AGBT23 ! Hear from 10x R&D including yours truly - we've been busy, and can't wait to share our updates with you. Today, 1:10 PM. Open-access livestream for those not at AGBT: tinyurl.com/5n75t72h

😍😍😍 Jill Herschleb showing data from a 1M cell per lane run for a total of 8M cells. She also teases this run included over 100 proteins with feature barcoding. #AGBT23

10x Genomics showing “the future of molecular cytometry” with a rapid Flex prep kit (8M cells in 6 minutes), and 137-plex protein tags with each cell’s transcriptome #AGBT23

Cell segmentation advances #AGBT23

Multiplex RNA/Protein #AGBT23

10x Genomics roadmap includes 5,000-plex RNA probes on Xenium imaging, and allele and Isoform mapping in situ; claim of no upper bound for density of RCA probes in situ #AGBT23

Now that plexy was cool but I think most the systems can theoretically get to >5K genes. BUT this isoform and snp level analysis is very cool. I don't see any other approch able to pull this off. 10x Genomics #AGBT23

In Situ Technology has come full circle! Originally pioneered and developed in the Nilsson lab, in situ analysis / sequencing has come home in the form of two Xenium In Situ platforms from 10x Genomics. Xenium will be offered as a service by Spatial Omics platform SciLifeLab

so Twitter is now just an infinite scroll of spam... great... much better now... glad we're all here