A new event on exciting breakthrough #tumour #research is now open for registration! Students are welcome to submit abstracts. conferences.nature.com/TumourLandscape In partnership with GeoffreyBeene_MSK @nature natureCancer Nature Reviews Cancer

#copper is important for cell plasticity and #inflammation. It enters cells via #CD44. nature nature.com/articles/s4158…

May the #rapamycin be with you! Pleased to be able to announce our new review on "Targeting the biology of aging with #mTOR inhibitors" with Joan Mannick now available at Nature Aging. Free-to-read link now available at nature.com/articles/s4358…

Cholera toxin: metabolic reprogramming of epithelial cells by a virulence factor changes the luminal environment of the microbiota. Nice example of how pathogens expose causal links between host physiology and gut microbiota composition. journals.asm.org/doi/10.1128/ia…

Septic shock and metastases: finding the culprits - ecancer ecancer.org/en/news/23077-…

RT UCL Laboratory for Molecular Cell Biology: A collaboration between Dr Sophie Acton and Sabrina Simoncelli lab sheds light on PDPN and CD44 action in FRCs using DNA-PAINT ow.ly/KW0R50OoKEC #OpenBiology

Great day with Peter Vandenabeele Universität Konstanz discussing #necroptosis #ferroptosis and mechanisms of membrane permeabilisation in #celldeath.

#CD44 is a regulator of cell plasticity chemistrycommunity.nature.com/posts/cd44-is-…

The career question I get asked the most is “why did I become a Physician-Scientist” - too often I give a vanilla answer to this - some colleagues have a Eureka moment- for me it was uncertainty, failure & extraordinary mentorship that set me on my journey nature.com/articles/s4301…

Derivative of #metformin called supformin can reduce #inflammation and cure #sepsis. New work published in nature nature.com/articles/s4158…

#CD44 regulates #iron #endocytocis in #cancer nature.com/articles/s4155…

Hey #MedStudentTwitter !! Easy one today. Bone marrow biopsy and a clinical image. Join the dots... Diagnosis? Management? #MedTwitter

Grateful to also be one of the recipients of these travel grants and I second Dr Anna Singleton She/Her - I wouldn’t be going to (my first international!) conference without this! So thank you to Cancer Institute NSW & to Mainthan Palendira and Dr Angela Ferguson for encouraging me to always apply for everything!!

Senescent Cells: A Therapeutic Target in Cardiovascular Diseases #Senolytic Digoxin Glutaminase 1 inhibitor Galactose-modified duocarmycin uPAR-specific CAR-T Senolytic vaccines▶️CD153 Antibody-drug conjugate▶️β2M Dr. James Kirkland lab Cells MDPI 2023 mdpi.com/2073-4409/12/9…

Our latest work showing that ferroptosis is initiated in lysosomes. nature.com/articles/s4158… #ferroptosis #iron