
Michael Fessler, MD
@fesslermd
Senior Investigator @NIEHS Intramural. Physician scientist. Heads #innateimmunity #Fesslerlab in RTP, NC. #Macrophage #Immunometabolism Opinions are my own.
ID: 1355337459131969545
30-01-2021 02:10:22
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165 Followers
144 Following

ASCI member Michael B. Fessler Michael Fessler, MD @NIEHS in JCI insight: 25-Hydroxycholesterol exacerbates vascular leak during acute lung injury: buff.ly/3KsSNov #Inflammation #Pulmonology


No #ENDO2023 live-tweeting for me this morning...because I'm chairing SY032, Orphan Nuclear Receptors at the Crossroads of Inflammation, Immunity, and Cancer. Come see 3 great talks from @EstebanezLab Michael Fessler, MD Michelle Williams, PhD starting at 10:30AM, McCormick W178A



Our study โฌ๏ธ Race specific association of IRGM risk allele (implicated in Crohns and other diseases), with increased cytokine expression in AAs. Bottom line: Underscores the importance of inclusion in genetic studies of immunity Michael Fessler, MD BCM Gastroenterology nature.com/articles/s4159โฆ

Our latest brief report: type i interferon is the key factor that drives susceptibility to intracellular bacterial infection in an autoimmune IRGM1-deficient mice ! #type1interferon #Fesslerlab Michael Fessler, MD Thanks to our collaborators ! ๐ Kat Mayer-Barber, PhD lab @ Greg Taylor lab


1/7 Latest paper in Cell Stem Cell! Transitional cell states sculpt tissue topology during lung regeneration. This work was jointly led by Arvind Konkimalla MD/PhD Satoshi Konishi Aleksandra Tata & Lauren with help from colleagues in our lab and collaborators @Duke tinyurl.com/4xhbm3zw


#WeekendRead! #InterferonPower ! Fessler &co show โฆJournal of Clinical Investigationโฉ that IRGM1 prevents excessive type I #IFN production & macrophages lytic death/necroptosis, allowing the differentiation of mature macrophages during bacterial infections! jci.org/articles/view/โฆ





