Just out!! Excited to see published our manuscript with Anika Gupta on the inference of regulatory relationships from stochastic transcriptional variation. Huge thanks to our mentors and all the coauthors!! pnas.org/doi/10.1073/pn…

#sciencetwitter what is your favorite way to fix cells for flow sorting and gDNA extraction? Methanol/ethanol, 1% formaldehyde, other?

The Goyal Lab is the first certified Green Lab at Northwestern University! Read more about our reasons for pursuing sustainability in our NU Sustainability write up: tinyurl.com/mr433h3n @yogeshgoyallab

Thrilled to share my PhD work in Cell! Massively parallel base editing to map variant effects in human hematopoiesis. We developed screens on blood stem cells to understand disease and develop treatments at single-nucleotide resolution.1/n cell.com/cell/fulltext/…

Can confirm the Goyal Lab is an incredibly supportive and rigorous learning environment with exciting conceptual projects.

Analyzing scRNAseq data. How can I be getting reads aligning to the 5' end of a transcript (SIV gag) when using a 10X 3' kit? Can these be real?

Congratulations to both first authors! A great resource.

We are excited to publish a spatially resolved single-cell multi-omic census of the placenta, contributing to the Human Cell Atlas project. The placenta plays an essential role in maintaining a healthy pregnancy, yet its function remains poorly understood. nature.com/articles/s4159…

One of my favorite stories is now preprinted, huge congrats to the authors!

I was blown away by the engagement and discussion at IIT Bombay during the Quantitative Bio of Collective Cell Behavior workshop this week, where I presented my project for the first time to an international audience. Huge thank you to Sayantan Dutta and Sanbed Das for hosting me!

Interesting read: Ben Kuznets-Speck shows how to combine causal perturbation data and generative models to uncover distinct gene sets driving subtypes of complex diseases. Nice! doi.org/10.1073/pnas.2…

Remarkable how well this simple, intuitive concept works to predict response to perturbation from unperturbed data. A little bit of physics goes a long way here!