🚨 Exciting news! 🚨 My first postdoc work on using highly correlated exposures for Mendelian Randomization (MR) is now in press AJHG! 🧬 We developed MVMR-cML-SuSiE and discovered that glutamine and lipids play key roles in Alzheimer's disease. cell.com/ajhg/abstract/… 1/n

New manuscript "Addressing the credibility crisis in Mendelian randomization" is out at BMC Medicine: bmcmedicine.biomedcentral.com/articles/10.11…. We discuss the explosion in MR studies, and what can be done by authors and editors/reviewers to improve the quality of published MR research. Thread:

Before submitting paper, we need to read this paper. It may be helpful. Prof Lennart Nacke, PhD PhD Voice - Independently Run Labiofy #PhDposition #phdlife #PhD #postdoc #chemtwitter

Hoy se votaba si es aceptable que a una persona joven le puedan pedir 1.000€ por una habitación, cobrarle los gastos de la inmobiliaria, y echarle al cabo de 11 meses. Junts, PP, VOX y UPN han votado que sí. Ni siquiera han permitido que haya debate. publico.es/politica/voto-…

Out today in The Lancet Neurology — we review excess brain volume loss following amyloid immunotherapy and conclude that it is *not* related to neuronal loss. Download here: authors.elsevier.com/c/1jnzE5FFzL0E… #ARPA Chris Belder The Lancet Neurology

1/ In medical school, I remember being both fascinated and terrified by prion diseases. Familial fatal insomnia in particular struck a chord. Why would a neurodegenerative prion disease cause someone to not be able to fall sleep? #medtwitter #tweetorial

Your biological age should NOT be ONE number. Introducing Ageome: our new framework that measures aging across thousands of molecular pathways simultaneously 🧬. Ageome challenges the single-number paradigm of biological age, offering a high-dimensional view of aging across

🗞️ A new study led by the BBRC reveals a non-linear link between telomere length and cognitive performance. 📢 The results indicate sex-specific associations, with shorter telomeres being associated with worse memory retrieval among women.

Fundación ”la Caixa” 🗨️ Blanca Rodríguez-Ferández (Blanca Rodríguez-Fernández 🏳️‍🌈🧬🧠), first author of the paper, explains the main highlights of the research in this video:

Doing good science is 90% finding a science buddy to constantly talk to about the project.

This study provides the first evidence that the aging phenotype is present at the mitochondrial level in iPSCs from aged donors, ranging from bioenergetics to mitochondrial network morphology.

mulea: An R package for enrichment analysis using multiple ontologies and empirical false discovery rate bmcbioinformatics.biomedcentral.com/articles/10.11…

Hay enfermedades que están "escondidas" a plena vista. Es el caso de la #DemenciaConCuerposDeLewy y claro, lo que no se conoce no se busca. Ojalá que con este reportaje consigamos darle visibilidad Asinlewy Estrella Morenas-Rodriguez SEN en La Razón ⤵️ larazon.es/salud/alguien-…

The Genetic NeuroEpi team is excited to be participating and learning at the Human Proteome conference in Dresden! Looking forward to new insights and connections! #HUPO2024

It is brilliant to see one of the first projects out of my lab now published on molecularpsychiatry! Congrats to Alex, all lab members and collaborators involved - and huge thanks to the participants and families, and all our funders! Enjoy the read: nature.com/articles/s4138…

Our new Nature Aging paper: We built 14 "biological clocks" representing the biological age and rate of aging of 14 major body systems using data from 13,000 people of the Human Phenotype Project Key findings: 1. Biological clocks are clinically meaningful: People with higher

THE DEFINITIVE AGING ATLAS in Science Magazine 🤯 A panoramic view of cell population dynamics in mammalian aging science.org/doi/10.1126/sc… PanSci, a single-cell transcriptome atlas profiling over 20 million cells from 623 mouse tissues across different life stages, sexes &

Now Online: Telomere function and regulation from mouse models to human ageing and disease go.nature.com/3D2Cu1m

Our GWAS meta-analysis on the genomic architecture of 40 circulating cytokines in 75,000 individuals is now out Communications Biology 🧬❗️ A short thread about the topline findings🧵

Late-onset epilepsy and neurodegeneration: intersecting mechanisms or separate entities? New scientific commentary by Xin You Tai and Marian Galovic tinyurl.com/563dwhbr