Ever wondered how dendritic cells that have never been at the site of a challenge know how to drive the right kind of T cell response? We did, and it’s finally come together! science.org/doi/10.1126/sc… Science Immunology

The August issue of Cancer Cell is now available: cell.com/cancer-cell/is…

Excited to see PhilippaMeiser's work being highlighted on the cover of this month's Cancer Cell issue 🤩

🎉Our Cancer immune archetype perspective is on Nature Reviews Cancer's July cover!. We're seeking a #postdoc to unravel the cellular networks and gene programs behind these archetypes. If you're fueled by passion for immunology and oncology 👉t.ly/0C3bB Please RT🙏

Dendritic cells can “self-shape” the chemotactic gradients that help them transport antigens to lymph nodes, finds a new live imaging study from Sixt Lab Edouard Hannezo. 📄: scim.ag/3Wv Focus by Hannah Donnelly Elena Mandrou Robert Insall: scim.ag/3Wu

Happy to share a link to our recent review of dendritic cells in cancer, written together with the great Mempel Lab Christopher Garris and MauroDiPilato. Here is a link giving full access to the paper: authors.elsevier.com/a/1hlQ83qNrUu3…

Fascinating discovery by @Annaglobig! Exhausted CD8 T cells talk to sympathetic nerves in tissues & tumors. Tex cells express ADRB1 and localize near sympathetic nerves, listening to stress hormone noradrenaline. This promotes their dysfunction. nature.com/articles/s4158…

Great talk by Sebastian Lacher from Jan P. Böttcher about how PGE2 perturbes anti-tumour responses by T cells 👏🏻 #SFIDGfI2023 DGfI - dgfi.org SFI Immunologie

OBS #Cancer #Immunology Seminar 📆 Tu, Oct 10, 12 pm ET/18 h CET 🎙️ Philippa Meiser PhilippaMeiser Jan P. Böttcher 🎙️ Dra Cristina Rius Rafael Moderator Julian Anthes Lisa Sevenich Lab Frankfurt Cancer Institute ✍️ us02web.zoom.us/meeting/regist… #openscience

Excited for the opportunity to share our research in tomorrow‘s Open Box Science seminar! There‘s still time to register 👇🏻

We are thrilled that our study on PGE2-mediated impairment of TCF1+ stem-like CD8+ T cell responses in cancer, with (twitterless) Sebastian Lacher as first author, is now published nature! 👇 a short 🧵 below! nature.com/articles/s4158…

Very happy to share our most recent endeavor into circadian anti-tumor immunity: Circadian tumor infiltration and function of CD8+ T cells dictate immunotherapy efficacy: Cell cell.com/cell/fulltext/…

The day has come 👨‍🎓I couldn’t be more grateful for the past years in the Jan P. Böttcher Thanks to everyone who was a part of this! 😇

Keeping up with traditions 😎 The Pittet Lab enjoying the science..and the fun at our annual #PATIM retreat 👩🏻‍🔬 thanks Janduslab Christoph Scheiermann Lab for organizing the event, it keeps getting better 🕺🏻

There's been amazing coverage of our new paper nature nature.com/articles/s4158… but I wanted to put together a walk-through (and make this accessible as possible). It's a bit long so get a cup of tea! The full version is open access so pls do have a read if you are interested...

We are excited that our study on the liver immune rheostat regulating CD8 T cell immunity in chronic HBV infection is published!🥳 @nature (nature.com/articles/s4158…)

How does oncogenic KRAS impact anti-tumor immunity in lung cancer? Out now in Cancer Research, using CRISPR screening we uncover COX-2/PGE2 signalling as a major mediator of immunotherapy resistance driven by oncogenic KRAS signaling. Jesse Boumelha The Crick aacrjournals.org/cancerres/arti…

First day of #EMBOcancerBio24 ending up with the hackathon session 🔥🔥 Great to see a vibrant spirit of collaboration to explore spatial transcriptomics data🚀🚀 Looking forward for the next two days ✨✨✨ Francesca Ciccarelli Maria Secrier Matteo Cereda The Crick

Learnt a lot at this great workshop! #EMBOcancerBio24 Going home with a lot of inspiration, ideas and the hackathon price 🥳 Feels like there’s still a lot to be discovered! EMBO The Crick

1/23 We are excited to announce that our most recent study “In vivo dendritic cell reprogramming for cancer immunotherapy” was published in Science Magazine. science.org/doi/10.1126/sc… Here is a summary of what we discovered!