Good news: our study of cell-intrinsic effects of CARD11 GOF in T cells is out in Frontiers - Immunology. Many thanks to all involved! Yogesh Jeelall Garvan Institute of Medical Research UNSW Medicine & Health Elissa Deenick Júlia Bier frontiersin.org/articles/10.33…

Congratulations to Phan Lab and collaborators, including multiple users of our INCITe centre. Here you can see the two upright #multiphoton #microscopes - Susie ZEISS Microscopy and Quatro #olympus- used in their #intravital #imaging work. Garvan Institute of Medical Research cell.com/cell/fulltext/…

that #macrophages residing in the follicle during resting state can mature into TBMs in the presence of apoptotic cells, even in the absence of germinal centers. ow.ly/PRHa50Nez27

Tingible body macrophages: Gargantuan chameleons of the germinal center. Elisa Baudon & Marc Bajenoff (bit.ly/3mUdBwQ) discuss recent reports from Neta Gurwicz, @zivshulman et al. bit.ly/3Y0RmCH & Grootveld et al. bit.ly/3ThEwyR

Many thanks to Laudon & Bajenoff Lab for their insightful commentary Journal of Experimental Medicine on Neta Gurwicz Ziv Shulman Lab Weizmann Institute and Abigail Grootveld Wunna Kyaw Garvan Institute of Medical Research in Cell on TBMs - the gargantuan chameleon of the germinal centre! rupress.org/jem/article/22…

So happy to see this out Journal of Experimental Medicine - epic effort led by Elissa Deenick #Scientia A/Prof UNSW Medicine & Health & Garvan Institute of Medical Research. PIK3R1 LOF & PIKCD GOF - same but diff't! Amazing collab with TangyeLab et al. Big congrats to 1st authors Nguyen, Lau & Júlia Bier! rupress.org/jem/article/22…

Happy to share our new review on “Mast cells in type 2 skin inflammation”European Journal of Immunology ! How are mast cells maintained and what do they do in atopic dermatitis? onlinelibrary.wiley.com/doi/10.1002/ej…

Looking forward to the first Australian Intravital Microscopy Symposium! Nov 23-24 2023, save the date! Garvan Institute of Medical Research

And that's a wrap! Lots of exciting science, interesting discussions and fun at the EMBO Imaging the Immune System in Lugano, Switzerland. Thanks to my co-organizers Cornelia Halin, Santiago Gonzalez and Jens Stein for the excellent job! See you in Wurzburg in 2025.

1/ How do you recover microenvironmental signals that drive cell differentiation from sc data? By taking the ENTRAIN! ENTRAIN is an environment-aware trajectory inference tool developed by Wunna Kyaw a brilliant PhD student Garvan Institute of Medical Research UNSW Medicine & Health. tinyurl.com/2vh2273d

Excited to share this protocol on how to do intravital imaging in the intact long bone! Thanks to Phan Lab for teaching and trusting me with this project. Grateful to Peter Croucher, Wunna Kyaw, Abigail Grootveld and the entire ACRF INCITe Centre team!

Finally dad's memoir will be out just in time for summer holiday reading with proceeds to go to UNSW Medicine & Health. Many thx to Interim Dean Adrienne Torda for hosting book launch December 14 VIPs incl mum, dad (& Thomas Keneally). Special pre-launch offer here: thebookadviser.com.au/product/fromvi…

Still vibing after a cracker day 1 at #AIMS2023 Garvan Institute of Medical Research. Australian intravital microscopy is THRIVING & it's awesome to be part of such a vibrant diverse community. Deep thoughtful science grounded in biology. Asking the hard questions. Can't wait for day 2 bring it on!

Congratulations again to Cristina Lo Celso for being awarded the Maria Goeppert Mayer Award 2023 And to our students Abigail Grootveld Daniel Reed Michael Trpceski and Marise van der Spuy winning the INCITe awards sponsored by Light Microscopy Aus and Cancer Institute NSW #AIMS2023

What is the function of alternative splicing in the proteome? What cellular functions does it impact? Our review (rdcu.be/dsryX) just published in NatureStructMolBiol suggests splicing impacts almost every cellular process. Fantastic work by Peter Kjer-Hansen! A short 🧵 below

Thank you Australasian Cell Death Society for this award!! Looking forward to presenting this work at the #ACDS seminar series next year!

Looking for an exciting new challenge in 2024? Deenick Lab is looking for postdoc keen to study the mechanisms of immunodeficiency and autoimmunity. Working with a great team of scientists in the precision immunology program Garvan Institute of Medical Research seek.com.au/job/72260172?t…

Congrats Wunna Kyaw Phan Lab & team Check out ENTRAIN here

Excited to contribute to April Issue Cancer Discovery. Led by Christine Chaffer & Peter Croucher Garvan Institute of Medical Research & Kathy Weilbaecher & Rebecca Aft Test Account we ask does chemoRx promote metastases through effects on immune microenvironments outside tumour ie EXTRA-TIME? tinyurl.com/4k6p9z39

Splice up your life! Excited to share our new Review on the potential of thinking protein isoforms when it comes to therapeutics! Link: rdcu.be/dSXxy Written with Weatheritt Lab Phan Lab A short overview🧵