New report from Massimiliano Zanin et al presents an organelle-interaction network analysis that "opens another critical dimension for a deeper characterization of various complex diseases with mitochondrial dysregulation" - focused on mitochondria in #Parkinsons nature.com/articles/s4154…

Some old saying: Great snow predicts a good year!

VIMP (VCP-interacting membrane protein), one of the 25 genes encoding selenoproteins in humans, as a gene regulating the effector functions of human CD4 T cells, especially production of several cytokines including IL2 and CSF2. cell.com/iscience/fullt…

Our work using Systems Immunology and Network-Biology methods to guide the discovery of a previously unrecognized role of Selenoprotein S (SELS or VIMP) in CD4 effector responses was just out: Cell Press iScience disq.us/t/3vexekw. LIH_Luxembourg ;uni.lu

No too much science, but only opinions just published in Brain, Behavior and Immunity. Several people from different countries with different religions believe that altruisticism guided from religions or culture could reward the brain and therefore play a more efficient role.

Standard PBMC cryopreservation selectively decreases detection of nine clinically-relevant T-cell markers biorxiv.org/cgi/content/sh… #bioRxiv

One work was just out. We believe it should have general impact on translational and clinical fields: Standard Peripheral Blood Mononuclear Cell Cryopreservation Selectively Decreases Detection of Nine Clinically Relevant T Cell Markers immunohorizons.org/content/5/8/711

You possibly hear too much about severe COVID-19. In fact, it is super important to understand the protective factors in mild patients. Deep immune profiling reveals early-stage and highly coordinated immune responses in mild COVID-19 patients medrxiv.org/content/10.110… Research Luxembourg

We found one gene, depletion of which slows down immunoaging, which was just out in EMBO Reports. embopress.org/doi/full/10.15…; This is a definitely long-term team effort. Thanks all for your great efforts! Research Luxembourg Luxembourg National Research Fund (FNR) Luxembourg Centre for Systems Biomedicine

If you are under stress, how does your immune system react? just out in Immunology onlinelibrary.wiley.com/doi/10.1111/im… Thanks to the excellent work of my best student Christophe and other colleagues! LIH_Luxembourg Luxembourg Centre for Systems Biomedicine Research Luxembourg

Another amazing cooperative work from Christophe and many partners just online Research Luxembourg Luxembourg Centre for Systems Biomedicine LNS - Laboratoire national de santé

I am thrilled to share our just published work in Nature Metabolism rdcu.be/cOoeU. We described a new pacemaker (DJ-1) of the pyruvate dehydrogenase (PDH) complex and its relevance in Treg homeostasis during ageing. Thank all the great partners. Luxembourg National Research Fund (FNR) Research Luxembourg

If you prefer this link: nature.com/articles/s4225… Luxembourg National Research Fund (FNR) Research Luxembourg LIH_Luxembourg Luxembourg Centre for Systems Biomedicine ; if you want to read the full text, you need to click the link in my original twitter.

The important thing should be repeated at least three times: official publication, just online by LIH_Luxembourg, Luxembourg Centre for Systems Biomedicine, just online by Nature Metabolism. #metabolism. Thanks again for all the outstanding partners. Happy to find something new in the fundamental biochemistry.

Wanna see the link between immune dysregulation & idiopathic neurodegenerative diseases (rdcu.be/drxwP). A milestone work, thanks to my former student, Christophe Capelle and all the partners, #NCER-PD consortium.Research Luxembourg Luxembourg National Research Fund (FNR) LIH_Luxembourg uni.lu #Parkinson

Combining computational prediction and experimental validation in human Tregs, in cooperation with Jorge Gonçalves computational team. Another longterm team efforts.Happy to share one of our recent systems immunology works nature.com/articles/s4154…. uni.lu LIH_Luxembourg Luxembourg National Research Fund (FNR)

Wanna know within first hours of treatment whether allergen-specific immunotherapy will work? Via systems immunology analysis in ~200 patient samples, we identify a uniform molecular pulse in those with the highest cure LIH_Luxembourg Luxembourg National Research Fund (FNR) Luxembourg Centre for Systems Biomedicine nature.com/articles/s4146…

Ever stung by bees or wasps or allergic to them. Take a look here. A decade of efforts. Luxembourg National Research Fund (FNR) Research Luxembourg

I’m honored to be serving as the immunosenescene collection’s Guest Editor of BMC Biology and eager to read your submission. LIH_Luxembourg , Luxembourg National Research Fund (FNR) yEFIS International Union of Immunological Societies BMC Biology, BMC, Research Luxembourg. See the link below.

Dear all, in case you missed the message below. International Union of Immunological Societies , yEFIS , BMC Biology , British Society for Immunology , The American Association of Immunologists (AAI). If you are interested in submitting one article, please find the submission link below. For reviews or perspectives, please first contact the editorial team.