I have two thoughts on H Pylori from stomach biopsies

1) How did the original pioneers think wow these are bacteria as opposed to “shmutz”

2) Sometimes, when it’s bad enough, you can diagnose H Pylori on routine H&E ⬇️

Credit: Rosemary Rodriguez, MD

#pathagonia #path4people

You don't need ROSE-colored glasses to diagnose this cerebellar tumor in a child. What is it? #pathology #neuropath #pathtwitter

Lung 🫁 development:

Embryonic (0-7 wk)
Pseudoglandular (8-17wk)
Canalicular (18-27 wk)
Saccular (28-36 wk)
Alveolar (37 wk- 2 yr)

Below is an unfortunate case from a 12 week old fetus.

#pathagonia #pathx #path4people #peds #peds x #pedipath #pathtwitter #medicine #embryology

Ouch!

Although benign, a subset of Serous Cystadenomas (SCAs) can grow & occlude the #pancreatic duct. In addition to VHL, these SCAs have mutations in TP53 & the hTERT promoter. Pic#3 in formalin to bring out their architecture. #Pathology #GIPath #Pancreas #PrecisionMedicine

1/2
2YOM with recurring seizures. Imaging shows large brain parenchymal mass-The surgeons say it appears 'extra axial'...attached to the falx but not infiltrating the brain.
This looks like embryonal tumour with abundant neuropil and rosettes (now ETMR) to me #CNSPath #Neuropath

Soy

Over diagnosis of melanoma.
Definitions.
Dr. David Elder

Int Soc Dermpath
#ISDP2024

#dermatopathology 🔬💕

Just spent all morning teaching #PlacentaPathology lab to the 2nd years. Kyla Jorgenson

Adrenal Cortex ~ (Top to Bottom of Picture): Capsule, Glomerulosa, Fasciculata, and Reticularis. #endocrine #pathology #adrenal #PathArt

Details of Michelangelo’s masterpiece “David” (1501–1504)

Organization in a Thrombus ~ #PathArt

#Pathology #Pediatrics 8 Y-old girl with MEN2B. Mucosal (gingival) neuromas.

Premature #fetalbrain with subependymal germinal matrix hemorrhage over the head of the #caudate nucleus. Etiologies include rich vascularity with immature capillaries and systemic hypoxia. #neuropath #neurotwitter #Neurology #autopsy #perinatalpath #PathTwitter #MedEd #pedpath

Paraganglioma v. Neuroendocrine Tumor 🤔

Both express neuroendocrine markers (eg. INSM-1), and nested architecture (see picture👇)

However, paragangliomas are (generally):
Cytokeratin negative
GATA3 positive.

#pathagonia #pathx #endocrinology #pedsx #medx #medicinex #gipath

54/M with Epstein anomaly and severe TR found a 6cm mass in RV by follow-up MRI. Endomyocardial biopsy revealed a cardiac DLBCL, EBV-negative, C-Myc FISH negative. More common in the right atrium. #CVpath #cardiacpath #hemepath #pathtwitter #pathresident

Join us for the SPP Spring 2024 Meeting on March 22nd & 23rd and experience the pinnacle of innovation and knowledge. Mark your calendars and ensure you're registered, because we're thrilled to present our featured speaker, Dr. Hiroyuki Shimada! 🔗 ow.ly/yaCU50QpOmn

Extramammary Paget Disease ~ #GYNpath #dermpath #pathology

La melanosis coli del día festivo 🤓

Stratum Lucidum ~ #PathArt