Accounting for 16S rRNA copy number prediction uncertainty and its implications in bacterial diversity analyses -in ISME Communications nature.com/articles/s4370…

Our conclusion is that IL-1b is a key axis that Salmonella uses to trick the host into helping establish colonization. Also, colonization levels in the gut do not correlate with mortality in mice. Most importantly, this taught us to not measure an outcome we don’t understand./19

Had a great time attending BIC2023 at UC Berkeley Was super fun getting to present some of our skin #microbiome work as a flash talk to an audience of #bioengineers working on many different topics! Happy to have secured the Best Rapid Talk award as well!😁🦠 #BIC2023

The only reason to care about #DaylightSavingTime is when you started a growth curve assay before the change, so now you need to remember to add that note about the change when taking the next time point to get the right growth rates. 🦠⏱️ #Microbiology

Our paper is out today in nature! Imagine getting this plot when studying single-cell data of growing bacteria! Could it be the cell cycle?! We found that a gene’s response to its replication reveals gene regulation on a genomic scale. nature.com/articles/s4158… Andrew Pountain

The Singapore Sting: Why an activist published a fake paper on ‘LGBTQ+ child acceptance.’ retractionwatch.com/2024/01/17/the…

DOE GSP PI Meeting 2024

How to pick a problem. Today in Cell. 1/53 cell.com/cell/fulltext/…

Reproducible #microbiome research of the skin 💪🏽🦠🌍 #skincareproducts #skinmicrobiome #metagenomics

We're hiring! We are seeking an exceptional postdoc associate to help us work on solving the antibiotic resistance crisis, details and apply here: broadinstitute.avature.net/en_US/careers/…

In our new paper at Cell (Cell), we reveal secrets of how the third form of life, archaea, make energy. We uncover new lineages of hydrogen-using enzymes, both minimal and complex. These help archaea thrive in all sorts of extreme environments. sciencedirect.com/science/articl…

Day 3 of the lab retreat- Cenotes and Maya ruins 🇲🇽

Behold SkinCom!!!! Exciting new avenue of translational microbiome research in the Karsten Zengler lab led by Asama Lekbua อสมา เล็กบัว and Deepan Thiruppathy now out in Cell Reports Methods—Fatemeh Askarian and Armin Kousha from our group helped establish the in vivo model cell.com/cell-reports-m…

Our latest preprint is out! This paper led by Sukhwan Yoon uncovers a new process controlling the global hydrogen and nitrogen cycles, i.e. the direct coupling of hydrogen oxidation and ammonification. A beautiful combination of isolation, bioreactor, and systems biology studies.

Today we report that an engineered skin bacterium, swabbed gently on the head of a mouse, can unleash a potent antibody response against a pathogen. Could lead to topical vaccines that are applied in a cream. Djenet Bousbaine led the charge... nature 1/55

The outer ear is a mammalian innovation but where did it come from? In our study in nature, Mathi Thiruppathy and colleagues find that the outer ear arose from modification of an ancestral gill program first originating in marine invertebrates. nature.com/articles/s4158… 1/n

It is finally out! Muntathar Al-Shimary, Doudna Lab, Brady Cress and I present a gene knockdown tool that works in diverse phages: CRISPRi through antisense RNA Targeting (CRISPRi-ART)! Check out the final paper in Nature Microbiology nature.com/articles/s4156…

Fish, Frogs, Friends, Lend me your Ears. 🐟🐸🐁🦎 Read this 'Behind the paper' story from Mathi Thiruppathy about her PhD work with Crump Lab: thenode.biologists.com/fish-frogs-fri… #DevBio #EvoDevo